CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028693
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Major urinary protein 5 
Protein Synonyms/Alias
 Major urinary proteins 11 and 8 
Gene Name
 Mup8 
Gene Synonyms/Alias
 Mup5; OTTMUSG00000008509 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
46TIILASDKREKIEDNacetylation[1]
46TIILASDKREKIEDNubiquitination[2]
49LASDKREKIEDNGNFacetylation[3]
49LASDKREKIEDNGNFubiquitination[2]
94MVADKTEKAGEYSVTubiquitination[2]
127MAHLINEKDGETFQLacetylation[3]
149PDLSSDIKERFAQLCubiquitination[2]
Reference
 [1] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Disulfide bond; Reference proteome; Secreted. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 180 AA 
Protein Sequence
MKMLLLLCVG LTLVCVHAEE ASSTGRNFNV EKINGEWHTI ILASDKREKI EDNGNFRLFL 60
EQIRVLENSL VLKVHTVRDE ECSELSMVAD KTEKAGEYSV TYDGFNTFTI PKTDYDNFLM 120
AHLINEKDGE TFQLMGLYGR EPDLSSDIKE RFAQLCEEHG ILRENIIDLS NANRCLQARE 180 
Gene Ontology
 GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
 GO:0005550; F:pheromone binding; IEA:InterPro.
 GO:0036094; F:small molecule binding; IEA:InterPro.
 GO:0005215; F:transporter activity; IEA:InterPro. 
Interpro
 IPR012674; Calycin.
 IPR011038; Calycin-like.
 IPR002345; Lipocalin.
 IPR022272; Lipocalin_CS.
 IPR000566; Lipocln_cytosolic_FA-bd_dom.
 IPR002971; Maj_urinary. 
Pfam
 PF00061; Lipocalin 
SMART
  
PROSITE
 PS00213; LIPOCALIN 
PRINTS
 PR00179; LIPOCALIN.
 PR01221; MAJORURINARY.