CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024898
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Enhancer of polycomb, isoform A 
Protein Synonyms/Alias
 Enhancer of polycomb, isoform B 
Gene Name
 E(Pc) 
Gene Synonyms/Alias
 CG7776; Dmel_CG7776 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
809AEELVGGKCEDQPVAacetylation[1]
1273ETANLPVKVEAVEKPacetylation[1]
1871YTSLLNVKPLQKNNSacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 2023 AA 
Protein Sequence
MSKLSFRARH LDPSKQMPIY LAEELPDLPE YSAINRAVPQ MPSGMEKEEE SEHHLQRAIC 60
TGLIIPTPEV LQTDQPFYDA YYPPDYKMPR QMIHMQPLGL DTEVPDYDMD SADEDWLSQQ 120
QRLELTELKF EQMMDRLEKS SGQTVVTLNE AKSLLNQDDE TSISVYDYWL NKRLKMQHPL 180
ILTVKTESRP GASSNNPYLA FRRRTEKMQT RKNRKNDEAS YEKMLKLRRD LQRATTILEM 240
VRRREETKRD HLKMTVNIFE KRVEMRDFNG AVYSELNSQY KNTRPAYNPL YTNQYSQGAA 300
AVGTAGAILA ALPTGLLPGG AGAAGNANVF GSASQYLNSS NLTMDAISGS GNGNSSRKEK 360
RPYKKRKHKL PRDKQQHQQQ QTQQHQQQQY LPASGGAGVS PAHHLPHHLH HLSRQQSASP 420
AANDSIADSE EEDYFGAGAQ NGNKLGSESE EETPFAFRRR SSCVYLPTRQ RDGRYPWDSA 480
DEDMAPSGAC SDAKYRYTLT SLNYPRPRCI GFARRRLGRG GRILLDRATT NFDDFWSQLD 540
YTVMESVTVN KCRDKIKQRD PDQLCKPSSP PTVVDLVPAG KPVDGEHPVP ELIKEEPSSD 600
TEKPVAATES GRESKERELE EKFENDVDDE FVASDDENVS RLGIYSSAVT LPQSCADLRQ 660
KRRRLRRKKQ QLRELNAAKR LKRSSEAVAT AEDVQLEDED TKPDLRPLPR AYLQRLALIL 720
GQKLKVEEDD NTEVSENVAP ELLEMNDPEQ LQPPRANHQQ HHRSNHNNNN NTVLNNNNSS 780
SSNVMNKDVS ISEKINVIKQ EAEELVGGKC EDQPVASTSA AAAAARAAEA AAAAEAASST 840
TTLAAPNPGP SLEEVAKTIK REMIDADDSN EPLSSIRTAA VMLSTQTSVS ELMDDEAEDD 900
VNLAQLSSII RHTAVKKELE AQQHQQQVQH EQMQAARKME EDEAAPCLNQ LPDVIRLRNI 960
RNSQVHARPK DLFVQAPVDE EFNADYMGGL SPTSSQRLDI CNELLSEIRR DWLHFRPKTP 1020
TDELSDSQDC EVGKTCDSHA VDWTQDTPIS VELNRLGKRE AEESDSSSYF LSSGFKYRDL 1080
ESDAQLLQTV QAQDYARGSS KSPNCSGSGS GSALEFNLSG GDSLNDINNL LGCDDEDDNH 1140
EHMLDNILQE CAMDDPKALN QATNFWNGIL DGEAAVDEVE MADQLLDCID EKKSKVGAAD 1200
TSKRAGRNRK ARLIQAPVGS SAFTVCPTAE TLKERELFFS QAPPVEVPPK EKTPAEVELP 1260
EVVVKETANL PVKVEAVEKP QSEVLPVAPQ PQQLQPQAIT LPTTQLINIP AQISTQKQHQ 1320
QPQVTQLLNQ FANAGPQIIA RTEYGGGAAV GDIVTITPHT GSSPLPTLTA QQQLQHQLAQ 1380
AQLRNVTVQQ RQATPQNPNQ NQNPQQQLLF QMQRDPSRSL TPLQAAGAGA TGNHLIYTTS 1440
CGEIVTAGAA ASASQKVTYA IQKAGVSSGG ATTASIGPNT VITLSNVKVQ NDDISSGGSG 1500
NSGSSVNIIN TASGQQLAVH SIAGMQQQGQ QQVQQVTTST PLLVATPTRN NVQQQQQQLV 1560
QQQPIVWRQV SGTNTAVATT AVLSTTVDSS PKAVTNQILW TSRATQKRQL NGPENTDINK 1620
LLLNRKLPRK QQIQQQHQQI QLTKQQLQQL VQHEELDDLV ATSTGNSGDQ METGDGLQQQ 1680
QQQQQQQQQL QKLSKVIKMS QFPLLVSDVS LQQQQSVSGQ AQQQQLKPNS AAAIAANHNY 1740
SLHPASTAII TAQATPQQAN KIFLTSSNSG GGGSAGNFTI ATASELQAAA AGQKLHYKEL 1800
PNSNLKLNFV SSAGTGEQTQ QVGATTVLLN KSQQQQQQQQ HQKLKTLATT GNSQTGQGDK 1860
RVLYTSLLNV KPLQKNNSGQ MQMQLGPGGL QQVLRGRLNN SAIITRTLPL GTTVNSTGGA 1920
VGPTTTTIRQ LVTTNANNVS SQDGNLLSAK EVGKALTVEQ VIASANNGGV VLPTSNNNNN 1980
NNGSGAGGNG GPLNSGVNAT GAGGGGSTGA GVGGAGVTST INR 2023 
Gene Ontology
 GO:0000123; C:histone acetyltransferase complex; IPI:FlyBase.
 GO:0005725; C:intercalary heterochromatin; NAS:FlyBase.
 GO:0032777; C:Piccolo NuA4 histone acetyltransferase complex; IEA:InterPro.
 GO:0005700; C:polytene chromosome; IDA:FlyBase.
 GO:0006325; P:chromatin organization; IMP:FlyBase.
 GO:0070983; P:dendrite guidance; IMP:FlyBase. 
Interpro
 IPR024943; Enhancer_polycomb.
 IPR019542; Enhancer_polycomb-like_N. 
Pfam
 PF10513; EPL1 
SMART
  
PROSITE
  
PRINTS