CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-032915
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Rho GTPase-activating protein 19 
Protein Synonyms/Alias
  
Gene Name
 ARHGAP19 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
48NPDFFVEKLRHEKPEubiquitination[1, 2]
105FRSLMSLKRKEKGVIubiquitination[1]
195PEPLLTHKHFNAHLKubiquitination[1]
302GSRTQASKDDLDLIAubiquitination[1, 2]
320TKSFQLAKSQKRNRVubiquitination[1]
361MPESAKKKQLIRQFNubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 465 AA 
Protein Sequence
MATEAQSEGE VPARESGRSD AICSFVICND SSLRGQPIIF NPDFFVEKLR HEKPEIFTEL 60
VVSNITRLID LPGTELAQLM GEVDLKLPGG AGPASGFFRS LMSLKRKEKG VIFGSPLTEE 120
GIAQIYQLIE YLHKNLRVEG LFRVPGNSVR QQILRDALNN GTDIDLESGE FHSNDVATLL 180
KMFLGELPEP LLTHKHFNAH LKIADLMQFD DKGNKTNIPD KDRQIEALQL LFLILPPPNR 240
NLLKLLLDLL YQTAKKQDKN KMSAYNLALM FAPHVLWPKN APAYIRECAR LHYLGSRTQA 300
SKDDLDLIAS CHTKSFQLAK SQKRNRVDSC PHQEETQHHT EEALRELFQH VHDMPESAKK 360
KQLIRQFNKQ SLTQTPGREP STSQVQKRAR SRSFSGLIKR KVLGNQMMSE KKKKNPTPES 420
VAIGELKGTS KENRNLLFSG SPAVTMTPTR LKWSEGKKEG KKAFV 465 
Gene Ontology
 GO:0005622; C:intracellular; IEA:InterPro.
 GO:0007165; P:signal transduction; IEA:InterPro. 
Interpro
 IPR008936; Rho_GTPase_activation_prot.
 IPR000198; RhoGAP_dom. 
Pfam
 PF00620; RhoGAP 
SMART
 SM00324; RhoGAP 
PROSITE
 PS50238; RHOGAP 
PRINTS