CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020677
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Adenylyl cyclase-associated protein 2 
Protein Synonyms/Alias
 CAP 2 
Gene Name
 Cap2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
62SMVAEFLKNSRVLAGubiquitination[1]
275NQGEAITKGLRHVTDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 May have a regulatory bifunctional role. 
Sequence Annotation
 DOMAIN 317 454 C-CAP/cofactor C-like.
 MOD_RES 261 261 Phosphoserine.  
Keyword
 Cell membrane; Complete proteome; Membrane; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 476 AA 
Protein Sequence
MTDMAGLMER LERAVIRLEQ LSAGLDGPPR GCGEVNGVNG GVAPSVEAFD KLINSMVAEF 60
LKNSRVLAGD VETHAEMVHG AFQAQRAFLL MVSQYQQPQE NEVAVLLKPI SEKIQEIQTF 120
RERNRGSNMF NHLSAVSESI AALGWIAVSP KPGPYVKEMN DAATFYTNRV LKDYKHSDLR 180
HVDWVRSYLN IWSELQAYIR EHHTTGLTWS KTGPVASTAS AFSILSSGPG LPPPPPPPPP 240
PGPPPPFENE DKKEEPSPSR SALFAQLNQG EAITKGLRHV TDDKKTYKNP SLRAQGQIRS 300
PTKTHTPSPT SPKSNSPQKH TPVLELEGKK WRVEYQEDRN DLVISETELK QVAYIFKCDK 360
STLQIKGKVN SITVDNCKKF GLVFDHVVGI VEVINSKDIQ IQVMGRVPTI SINKTEGCHL 420
YLSEDALDCE IVSAKSSEMN VLVPQDDDYR EFPIPEQFKT IWDGSKLVTE PAEIMA 476 
Gene Ontology
 GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
 GO:0000902; P:cell morphogenesis; IEA:InterPro.
 GO:0007010; P:cytoskeleton organization; IEA:InterPro. 
Interpro
 IPR001837; Adenylate_cyclase-assoc_CAP.
 IPR013912; Adenylate_cyclase-assoc_CAP_C.
 IPR013992; Adenylate_cyclase-assoc_CAP_N.
 IPR017901; C-CAP_CF_C-like.
 IPR016098; CAP/MinC_C.
 IPR018106; CAP_CS.
 IPR006599; CARP_motif. 
Pfam
 PF08603; CAP_C
 PF01213; CAP_N 
SMART
 SM00673; CARP 
PROSITE
 PS51329; C_CAP_COFACTOR_C
 PS01088; CAP_1
 PS01089; CAP_2 
PRINTS