CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011413
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 LETM1 domain-containing protein YLH47, mitochondrial 
Protein Synonyms/Alias
 LETM1 homolog 
Gene Name
 YLH47 
Gene Synonyms/Alias
 MRS7; YPR125W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
200KNNKSHFKPNNISEEacetylation[1]
443DVKPHDTKPIGEAAAacetylation[1]
Reference
 [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 
Functional Description
 Involved in mitochondrial potassium homeostasis through the mitochondrial K(+)/H(+) exchange regulation (By similarity). 
Sequence Annotation
 DOMAIN 78 344 LETM1.  
Keyword
 Coiled coil; Complete proteome; Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 454 AA 
Protein Sequence
MLKYRSLPIK RAIHHPAPGI TPISPRIMVS RLRVIPSFNL KFNRWNSSVP ESSKKELKTT 60
DGNQESASKV SPVKEKEKVP FKVKMQKALR HYWDGSKLLG LEIKISSKLL MKSAAGYPLT 120
RRENLQLKRT TQDIVRLVPF AAFLIIPFAE LLLPFALKLF PNLLPSTYES SKKRENKLEN 180
LRNTRKLMSE IIKNNKSHFK PNNISEEQKA LFNRFYTHVR ATGVPESRQQ LIEVARLFTD 240
DTVLDNVTRP YLIALAKYMN LQPFGTDVML RYRIRYKMLE LKKDDLSIYY EDAEQLSLSE 300
LKTACASRGI RSVDVEPSVL YSNLRLWLNM RLKDKIPSTL LIMATAYNYG NVQSKESLYD 360
ALCDVLIGIP DELYHEVKVN VVKEDEASAK QKLKQLREQE EIMKEEEQQE ENAIVSVKDE 420
LSLDDQDKNI DAAAPDVKPH DTKPIGEAAA IKEK 454 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005743; C:mitochondrial inner membrane; IDA:SGD.
 GO:0006813; P:potassium ion transport; IGI:SGD.
 GO:0051204; P:protein insertion into mitochondrial membrane; IMP:SGD.
 GO:0015992; P:proton transport; IGI:SGD. 
Interpro
 IPR011685; LETM1. 
Pfam
 PF07766; LETM1 
SMART
  
PROSITE
  
PRINTS