UniProt Accession

 IPP2_RAT; P50411; Q56A32 

Genbank Protein ID

 S79213; BC092194 

Genbank Nucleotide ID

 AAB35244.1; AAH92194.1 

Protein Name

 Protein phosphatase inhibitor 2 

Protein Synonyms/Alias

 IPP-2 

Gene Name

 Ppp1r2 

Gene Synonyms/Alias

 Ipp2 

Created Date

 July 27, 2013 

Organism

 Rattus norvegicus (Rat) 

NCBI Taxa ID

 10116 

Lysine Modification

Position	Peptide	Type	References
12	TASHRPIKGILKNKT	acetylation	[1]
163	LARQLISKDLHDDDE	acetylation	[1]

Reference

 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 

Functional Description

 Inhibitor of protein-phosphatase 1. 

Sequence Annotation

 REGION 12 17 Required for binding PPP1CC (By
 REGION 43 55 Required for binding PPP1CC (By
 REGION 147 150 Required for binding PPP1CC catalytic
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 44 44 Phosphoserine; by ATM (By similarity).
 MOD_RES 73 73 Phosphothreonine; by GSK3 (By
 MOD_RES 87 87 Phosphoserine (By similarity).
 MOD_RES 121 121 Phosphoserine (By similarity).
 MOD_RES 122 122 Phosphoserine (By similarity).  

Keyword

 Acetylation; Carbohydrate metabolism; Complete proteome; Glycogen metabolism; Phosphoprotein; Protein phosphatase inhibitor; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 205 AA 

Protein Sequence

Gene Ontology

 GO:0004864; F:protein phosphatase inhibitor activity; IEA:UniProtKB-KW.
 GO:0005977; P:glycogen metabolic process; IEA:UniProtKB-KW.
 GO:0043666; P:regulation of phosphoprotein phosphatase activity; IEA:InterPro.
 GO:0009966; P:regulation of signal transduction; IEA:InterPro. 

Interpro

 IPR007062; PPI-2. 

Pfam

 PF04979; IPP-2 

SMART

  

PROSITE

  

PRINTS