CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028563
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 MBT domain-containing protein 1 
Protein Synonyms/Alias
  
Gene Name
 Mbtd1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
69VRDAFYSKTKRFCSVacetylation[1]
115QKQPLVAKLAAYAQYacetylation[1, 2]
Reference
 [1] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 504 AA 
Protein Sequence
MFDGYDSCSE DTSSSSSSEE SEEEVAPLPS NLPIIKNNGQ VYTYPDGKSG MATCEMCGMV 60
GVRDAFYSKT KRFCSVSCSR SYSSNSKKAS ILARLQGKPP TKKAKVLQKQ PLVAKLAAYA 120
QYQATLQNQA KTKAGNSAIS VEGFSWGNYI NSNSFIAAPV ACFKHAPMGT CWGDISENVR 180
IEVPNTDCSL PTKVFWIAGI IKLAGYNALL RYEGFENDSS LDFWCNICGS DIHPVGWCAA 240
SGKPLVPPRT VQHKYTNWKA FLVKRLTGAK TLPPDFSQKV SESMQYPFKP CMRVEVVDKR 300
HLCRTRVAVV ESVIGGRLRL VYEESEDRTD DFWCHMHSPL IHHIGWSRSI GHRFKRSDIT 360
KKQDGHFDTP PHLFAKVKEV DQSGEWFKEG MKLEAIDPLN LSTICVATIR KVLADGFLMI 420
GIDGSEAADG SDWFCYHATS PSIFPVGFCE INMIELTPPR GTPFWYKHSV SSLALFLCVN 480
LLTFNIALIL VVVRVFIHSM YEYV 504 
Gene Ontology
 GO:0005634; C:nucleus; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0048706; P:embryonic skeletal system development; IMP:MGI.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:InterPro. 
Interpro
 IPR004092; Mbt.
 IPR012313; Znf_FCS. 
Pfam
 PF02820; MBT 
SMART
 SM00561; MBT 
PROSITE
 PS51079; MBT
 PS51024; ZF_FCS 
PRINTS