CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028163
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Serine/threonine-protein kinase RIO1 
Protein Synonyms/Alias
  
Gene Name
 CG11660, Dmel_CG11660 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
323DVELSTSKARELYRDacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; Serine/threonine-protein kinase; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 585 AA 
Protein Sequence
MNNDSHKYSD AEEDEEDLRS SEWTNDFKNL TLKHEIFKDI KLTPKEDCDD LAQVIATANE 60
EDEPEDEEPE EYDEDDYDDI GDDYDTYEEA YTGFNKLHVQ PQLTNASGGG SGGGAGGASG 120
GSQRVSSYQP NEKLLRRYSA RINVEKYDPT TNMSAQAANR LVNFDRRDRT QVRDKHDRAT 180
AEQVMDPRTR MILFKLLNRG MIQEINGCIS TGKEANVYHA VSKNGEEEFA IKIYKTSILV 240
FKDRDKYVSG EFRFRHGYCK HNPRKMVRTW AEKEMRNYLR MRNAGVPVPE PILLRSHVLV 300
MRFCGRDGWP APKLKDVELS TSKARELYRD CVVIMWRIYN QCRLVHADLS EFNILLQDGQ 360
LVIIDVSQSV EHDHPHSFDF LRKDCTNISE FFRKRAVATM TVKELFDFIT DQTITTENME 420
ECLERISERI KDRDFDAISA QEKIDEAVWQ NTYIPKRLDE VRHFERDVAK AKQGVQQNLI 480
YGKITGLTSD LDVQQKPDVL QSSTAKEDDG SEAQTSGSED EDNSQDNDND EDAKKFKNSA 540
RPREESPESK KARKKAVKDA KAEQRKVKVK KHVKKRKEKM GSMKK 585 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-KW.
 GO:0022008; P:neurogenesis; IMP:FlyBase. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR018934; RIO-like_kinase.
 IPR000687; RIO_kinase.
 IPR018935; RIO_kinase_CS.
 IPR017407; Ser/Thr_kinase_Rio1. 
Pfam
 PF01163; RIO1 
SMART
 SM00090; RIO 
PROSITE
 PS01245; RIO1 
PRINTS