UniProt Accession

 H0YE88_HUMAN; H0YE88 

Genbank Protein ID

 AC013549; AC084859; AC107881 

Genbank Nucleotide ID

  

Protein Name

 Transcriptional enhancer factor TEF-1 

Protein Synonyms/Alias

  

Gene Name

 TEAD1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
65	IILSDEGKMYGRNEL	ubiquitination	[1]

Reference

 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 426 AA 

Protein Sequence

Gene Ontology

 GO:0005634; C:nucleus; IEA:Compara.
 GO:0003677; F:DNA binding; IEA:Compara.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:Compara.
 GO:0003143; P:embryonic heart tube morphogenesis; IEA:Compara.
 GO:0035329; P:hippo signaling cascade; IEA:Compara.
 GO:0048368; P:lateral mesoderm development; IEA:Compara.
 GO:0030903; P:notochord development; IEA:Compara.
 GO:0048339; P:paraxial mesoderm development; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0042127; P:regulation of cell proliferation; IEA:Compara. 

Interpro

 IPR000818; TEA/ATTS.
 IPR016361; TEF. 

Pfam

 PF01285; TEA 

SMART

 SM00426; TEA 

PROSITE

 PS00554; TEA_1
 PS51088; TEA_2 

PRINTS

 PR00065; TEADOMAIN.