UniProt Accession

 A8MXR3_HUMAN; A8MXR3 

Genbank Protein ID

 AP000339; AP000340 

Genbank Nucleotide ID

  

Protein Name

 Protein arginine N-methyltransferase 2 

Protein Synonyms/Alias

  

Gene Name

 PRMT2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
56	LSFLRGEKILILRQT	ubiquitination	[1]
86	IPANHVGKHVDEYDP	ubiquitination	[1, 2]
124	ADQPRTTKYHSVILQ	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Methyltransferase; Reference proteome; SH3 domain; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 253 AA 

Protein Sequence

Gene Ontology

 GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
 GO:0006479; P:protein methylation; IEA:InterPro. 

Interpro

 IPR025799; Arg_MeTrfase.
 IPR001452; SH3_domain.
 IPR007848; Small_mtfrase_dom. 

Pfam

 PF05175; MTS
 PF00018; SH3_1 

SMART

 SM00326; SH3 

PROSITE

 PS50002; SH3 

PRINTS

 PR00452; SH3DOMAIN.