CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007182
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nucleolar complex protein 2 
Protein Synonyms/Alias
  
Gene Name
 NOC2 
Gene Synonyms/Alias
 YOR206W; YOX001 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
45GNKTDQEKADAAGTRubiquitination[1]
120SMAKLAEKDPEFYKYacetylation[2]
384MPLINFQKNSAAELFmethylation[3]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [3] Identification of arginine- and lysine-methylation in the proteome of Saccharomyces cerevisiae and its functional implications.
 Pang CN, Gasteiger E, Wilkins MR.
 BMC Genomics. 2010 Feb 5;11:92. [PMID: 20137074] 
Functional Description
 Involved in the intranuclear transport of ribosomal precursors. 
Sequence Annotation
 MOD_RES 70 70 Phosphoserine.
 MOD_RES 149 149 Phosphoserine.
 MOD_RES 160 160 Phosphoserine.
 MOD_RES 166 166 Phosphoserine.
 MOD_RES 698 698 Phosphoserine.
 MOD_RES 708 708 Phosphoserine.  
Keyword
 Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Ribosome biogenesis. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 710 AA 
Protein Sequence
MGKVSKSTKK FQSKHLKHTL DQRRKEKIQK KRIQGRRGNK TDQEKADAAG TREQQQLKKS 60
AKEEVFKDMS VETFFEKGIE IPKENKKLKK KTTKEQSDED SSSSEEEEDM GQSMAKLAEK 120
DPEFYKYLEE NDKDLLDFAG TNPLDGIDSQ DEGEDAERNS NIEEKSEQME LEKEKIELSL 180
KLVRKWKKQL HDSPSLKLLR NIISAFKVAV NLNKEENIED YKYAITDEKA FHELMFMVLK 240
DVPQAIQKMA PYKIVKGART LPNGGNVSRV SSIVKSHAGS LLILLNDITN TETAALVLHS 300
VNELMPYLLS YRRILKELIK SIVGVWSTTR ELETQIASFA FLINTTKEFK KSMLETTLKT 360
TYSTFIKSCR KTNMRSMPLI NFQKNSAAEL FGIDEVLGYQ VGFEYIRQLA IHLRNTMNAT 420
TKKSSKINSA EAYKIVYNWQ FCHSLDFWSR VLSFACQPEK ENGSESPLRQ LIYPLVQVTL 480
GVIRLIPTPQ FFPLRFYLIK SLIRLSQNSG VFIPIYPLLS EILTSTAFTK APKKSPNLAA 540
FDFEHNIKCT QAYLNTKIYQ EGLSEQFVDL LGDYFALYCK NIAFPELVTP VIISLRRYIK 600
TSTNVKLNKR LSTVVEKLNQ NSTFIQEKRS DVEFGPTNKS EVSRFLNDVA WNKTPLGSYV 660
AVQREVKEEK ARLMRESMEE QDKERETEEA KLLNSLESDD DNEDVEMSDA 710 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:SGD.
 GO:0030690; C:Noc1p-Noc2p complex; IPI:SGD.
 GO:0030691; C:Noc2p-Noc3p complex; IPI:SGD.
 GO:0005730; C:nucleolus; IEA:UniProtKB-SubCell.
 GO:0000054; P:ribosomal subunit export from nucleus; TAS:SGD.
 GO:0042255; P:ribosome assembly; TAS:SGD. 
Interpro
 IPR005343; Noc2. 
Pfam
 PF03715; Noc2 
SMART
  
PROSITE
  
PRINTS