Tag | Content |
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CPLM ID | CPLM-011392 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Pre-rRNA-processing protein ESF1 |
Protein Synonyms/Alias | 18S rRNA factor 1 |
Gene Name | ESF1 |
Gene Synonyms/Alias | YDR365C |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
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23 | AGIYSDPKFKNTKTK | acetylation | [1] | 55 | QHKSKVDKYGRKIKN | acetylation | [1] | 482 | NDEEEIEKNAKSKAE | acetylation | [1] |
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Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Involved in the 18S rRNA synthesis. Required for the early cleavages at sites A0, A1 and A2. |
Sequence Annotation | MOD_RES 86 86 Phosphoserine. MOD_RES 220 220 Phosphothreonine. MOD_RES 223 223 Phosphoserine. MOD_RES 225 225 Phosphoserine. MOD_RES 367 367 Phosphoserine. MOD_RES 369 369 Phosphoserine. MOD_RES 372 372 Phosphoserine. MOD_RES 542 542 Phosphothreonine. |
Keyword | Coiled coil; Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Ribosome biogenesis; RNA-binding; rRNA processing. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 628 AA |
Protein Sequence | MAGENPKKEG VDARFAGIYS DPKFKNTKTK DHKIKLDSRF SKKDLEVQHK SKVDKYGRKI 60 KNAQNNRELE DFDKYFEKEA ENDEDSEVNA KTVVDRARGE VPDDYVSSSD EFTSSDSESS 120 GESEVESEEE NEVEIENAKP ESGDISKNLA VVNLDWDHVK SEDLMITFSS FVPKGGKIER 180 VAIYPSEFGK ERMQREEVEG PPKELFQKKN KNKTSKKKKT DDSDSDMDIG IKDLYEEGDA 240 DKDVDSRALR QYQLDRLRYY YAIVYCSDTT TSKAIYDNCD GTEYESTANM FDLRYVPDGM 300 TFDDDVRDEC SILPKNYRPH QFSTDALQHS SVKLTWDETP ADRVEVAKRA FTQKEIDDMD 360 FKAYLASDSD ESDGQVDEEA KNKLKSLVGD FGFNSKKETP NDEDEEVDME ITFTPALEGG 420 NEKSSEDKEE TTIEKIRRKE KERRKARKQK VKELKQQSEK DKKSKLKSVN KKHTNDEEEI 480 EKNAKSKAEL ELLMDDDDDT ETQGTINNKA HFNMNEILRS EKEKHKKGRY QKKERIVEDT 540 FTPDLEDPRF KEVFEDHDFA IDPTQPEFKG TQAMSKILKE RSKRVKNKKR KLGGSENNMT 600 NNADDNEDIG NLVNKLKKKS KSSKKVKV 628 |
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