| Tag | Content |
|---|
| CPLM ID | CPLM-009337 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Syntaxin-1B |
Protein Synonyms/Alias | |
Gene Name | Stx1b |
Gene Synonyms/Alias | Stx1b1; Stx1b2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 45 | EIRGCIEKLSEDVEQ | ubiquitination | [1] | | 54 | SEDVEQVKKQHSAIL | ubiquitination | [1] | | 55 | EDVEQVKKQHSAILA | ubiquitination | [1] | | 69 | AAPNPDEKTKQELED | ubiquitination | [1] | | 71 | PNPDEKTKQELEDLT | ubiquitination | [1] | | 82 | EDLTADIKKTANKVR | ubiquitination | [1] | | 93 | NKVRSKLKAIEQSIE | ubiquitination | [1] | | 125 | QHSTLSRKFVEVMTE | ubiquitination | [1] | | 139 | EYNATQSKYRDRCKD | ubiquitination | [1] | | 172 | EDMLESGKLAIFTDD | ubiquitination | [1] | | 181 | AIFTDDIKMDSQMTK | ubiquitination | [1] | | 188 | KMDSQMTKQALNEIE | ubiquitination | [1] | | 203 | TRHNEIIKLETSIRE | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Potentially involved in docking of synaptic vesicles at presynaptic active zones (By similarity). May mediate Ca(2+)- regulation of exocytosis acrosomal reaction in sperm. |
Sequence Annotation | DOMAIN 191 253 t-SNARE coiled-coil homology.
MOD_RES 14 14 Phosphoserine.
MOD_RES 58 58 Phosphoserine.
MOD_RES 160 160 Phosphothreonine. |
Keyword | Coiled coil; Complete proteome; Direct protein sequencing; Membrane; Neurotransmitter transport; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 288 AA |
Protein Sequence | MKDRTQELRS AKDSDDEEEV VHVDRDHFMD EFFEQVEEIR GCIEKLSEDV EQVKKQHSAI 60
LAAPNPDEKT KQELEDLTAD IKKTANKVRS KLKAIEQSIE QEEGLNRSSA DLRIRKTQHS 120
TLSRKFVEVM TEYNATQSKY RDRCKDRIQR QLEITGRTTT NEELEDMLES GKLAIFTDDI 180
KMDSQMTKQA LNEIETRHNE IIKLETSIRE LHDMFVDMAM LVESQGEMID RIEYNVEHSV 240
DYVERAVSDT KKAVKYQSKA RRKKIMIIIC CVVLGVVLAS SIGGTLGL 288 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0016020; C:membrane; IDA:MGI. GO:0006886; P:intracellular protein transport; IEA:InterPro. GO:0006836; P:neurotransmitter transport; IEA:UniProtKB-KW. GO:0017157; P:regulation of exocytosis; IEA:Compara. GO:0007268; P:synaptic transmission; IEA:InterPro. GO:0016192; P:vesicle-mediated transport; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |