CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031655
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Diacylglycerol kinase beta 
Protein Synonyms/Alias
  
Gene Name
 DGKB 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
407SGSQQPNKVIDKNKMmethylation[1]
Reference
 [1] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 803 AA 
Protein Sequence
MTNQEKWAHL SPSEFSQLQK YAEYSTKKLK DVLEEFHGNG VLAKYNPEGK QDILNQTIDF 60
EGFKLFMKTF LEAELPDDFT AHLFMSFSNK FPHSSPMVKS KPALLSGGLR MNKGAITPPR 120
TTSPANTCSP EVIHLKDIVC YLSLLERGRP EDKLEFMFRL YDTDGNGFLD SSELENIISQ 180
MMHVAEYLEW DVTELNPILH EMMEEIDYDH DGTVSLEEWI QGGMTTIPLL VLLGLENNVK 240
DDGQHVWRLK HFNKPAYCNL CLNMLIGVGK QGLCCSFCKY TVHERCVARA PPSCIKTYVK 300
SKRNTDVMHH YWVEGNCPTK CDKCHKTVKC YQGLTGLHCV WCQITLHNKC ASHLKPECDC 360
GPLKDHILPP TTICPVVLTL PTSGVSVPEE RQSTVKKEKS GSQQPNKVID KNKMQRANSV 420
TVDGQGLQVT PVPGTHPLLV FVNPKSGGKQ GERIYRKFQY LLNPRQVYSL SGNGPMPGLN 480
FFRDVPDFRV LACGGDGTVG WVLDCIEKAN VGKHPPVAIL PLGTGNDLAR CLRWGGGYEG 540
ENLMKILKDI ENSTEIMLDR WKFEVIPNDK DEKGDPVPYS IINNYFSIGV DASIAHRFHI 600
MREKHPEKFN SRMKNKFWYF EFGTSETFSA TCKKLHESVE IECDGVQIDL INISLEGIAI 660
LNIPSMHGGS NLWGESKKRR SHRRIEKKGS DKRTTVTDAK ELKFASQDLS DQLLEVVGLE 720
GAMEMGQIYT GLKSAGRRLA QCSCVVIRTS KSLPMQIDGE PWMQTPCTIK ITHKNQAPML 780
MGPPPKTGLF CSLVKRTRNR SKE 803 
Gene Ontology
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004143; F:diacylglycerol kinase activity; IEA:InterPro.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR000756; Diacylglycerol_kin_accessory.
 IPR001206; Diacylglycerol_kinase_cat_dom.
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR002219; Prot_Kinase_C-like_PE/DAG-bd. 
Pfam
 PF00130; C1_1
 PF00609; DAGK_acc
 PF00781; DAGK_cat
 PF13499; EF_hand_5 
SMART
 SM00109; C1
 SM00045; DAGKa
 SM00046; DAGKc
 SM00054; EFh 
PROSITE
 PS50146; DAGK
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS00479; ZF_DAG_PE_1
 PS50081; ZF_DAG_PE_2 
PRINTS