UniProt Accession

 H0YNW5_HUMAN; H0YNW5 

Genbank Protein ID

 AC023355 

Genbank Nucleotide ID

  

Protein Name

 Deoxyuridine 5'-triphosphate nucleotidohydrolase, mitochondrial 

Protein Synonyms/Alias

  

Gene Name

 DUT 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
94	PRSGLAAKHFIDVGA	ubiquitination	[1]
166	GGFGSTGKN******	acetylation	[2]
166	GGFGSTGKN******	ubiquitination	[2, 3, 4]

Reference

 [1] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 167 AA 

Protein Sequence

Gene Ontology

 GO:0004170; F:dUTP diphosphatase activity; IEA:InterPro.
 GO:0046080; P:dUTP metabolic process; IEA:InterPro. 

Interpro

 IPR008180; dUTP_pyroPase.
 IPR008181; dUTP_pyroPase_sf. 

Pfam

 PF00692; dUTPase 

SMART

  

PROSITE

  

PRINTS