CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-016671
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DCN1-like protein 2 
Protein Synonyms/Alias
 DCUN1 domain-containing protein 2; Defective in cullin neddylation protein 1-like protein 2 
Gene Name
 Dcun1d2 
Gene Synonyms/Alias
 Dcun1l2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
149PRLEQELKDPAKFKDubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May contribute to neddylation of cullin components of SCF-type E3 ubiquitin ligase complexes. Neddylation of cullins play an essential role in the regulation of SCF-type complexes activity (By similarity). 
Sequence Annotation
 DOMAIN 8 45 UBA-like.
 DOMAIN 60 248 DCUN1.  
Keyword
 Alternative splicing; Complete proteome; Reference proteome; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 259 AA 
Protein Sequence
MHKLKSAQKD KVRQFMACTQ ASERTAIYCL TQNEWKLDEA TDSFFQNPEA FHRESMKSSV 60
DQKKLEQLYS RYKDPQDENK IGIDGIQQFC DDLSLDPASI SVLVIAWKFR AATQCEFSKK 120
EFVDGMTELG CDSTERLKAL LPRLEQELKD PAKFKDLYQF TFTFAKNPGQ KGLDLEMAVA 180
YWKLVLSGRF KFLDLWNTFL LEHHKRSIPR DTWNLLLDFG NMIADDLSNY DEEGAWPVLI 240
DDFVEYARPV VTGGRRSPF 259 
Gene Ontology
  
Interpro
 IPR014764; DCN-prot.
 IPR005176; PONY_dom.
 IPR009060; UBA-like. 
Pfam
 PF03556; Cullin_binding 
SMART
  
PROSITE
 PS51229; DCUN1 
PRINTS