| Tag | Content |
|---|
| CPLM ID | CPLM-017011 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Choline transporter-like protein 2 |
Protein Synonyms/Alias | Solute carrier family 44 member 2 |
Gene Name | SLC44A2 |
Gene Synonyms/Alias | CTL2; PSEC0210 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 17 | GKHGTPQKYDPTFKG | ubiquitination | [1] | | 209 | TDLVEGAKKANGVLE | ubiquitination | [1] | | 406 | SPCPFTAKTCNPETF | ubiquitination | [1] | | 481 | SYYWALRKPDDLPAF | ubiquitination | [1] | | 693 | YFMSSTLKKLLNKTN | ubiquitination | [1] |
|
Reference | [1] Systematic and quantitative assessment of the ubiquitin-modified proteome. Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP. Mol Cell. 2011 Oct 21;44(2):325-40. [ PMID: 21906983] |
Functional Description | Isoform 1, but not isoform 3, exhibits some choline transporter activity. |
Sequence Annotation | CARBOHYD 187 187 N-linked (GlcNAc...).
CARBOHYD 200 200 N-linked (GlcNAc...).
CARBOHYD 417 417 N-linked (GlcNAc...) (Potential). |
Keyword | Alternative promoter usage; Alternative splicing; Complete proteome; Glycoprotein; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 706 AA |
Protein Sequence | MGDERPHYYG KHGTPQKYDP TFKGPIYNRG CTDIICCVFL LLAIVGYVAV GIIAWTHGDP 60
RKVIYPTDSR GEFCGQKGTK NENKPYLFYF NIVKCASPLV LLEFQCPTPQ ICVEKCPDRY 120
LTYLNARSSR DFEYYKQFCV PGFKNNKGVA EVLQDGDCPA VLIPSKPLAR RCFPAIHAYK 180
GVLMVGNETT YEDGHGSRKN ITDLVEGAKK ANGVLEARQL AMRIFEDYTV SWYWIIIGLV 240
IAMAMSLLFI ILLRFLAGIM VWVMIIMVIL VLGYGIFHCY MEYSRLRGEA GSDVSLVDLG 300
FQTDFRVYLH LRQTWLAFMI ILSILEVIII LLLIFLRKRI LIAIALIKEA SRAVGYVMCS 360
LLYPLVTFFL LCLCIAYWAS TAVFLSTSNE AVYKIFDDSP CPFTAKTCNP ETFPSSNESR 420
QCPNARCQFA FYGGESGYHR ALLGLQIFNA FMFFWLANFV LALGQVTLAG AFASYYWALR 480
KPDDLPAFPL FSAFGRALRY HTGSLAFGAL ILAIVQIIRV ILEYLDQRLK AAENKFAKCL 540
MTCLKCCFWC LEKFIKFLNR NAYIMIAIYG TNFCTSARNA FFLLMRNIIR VAVLDKVTDF 600
LFLLGKLLIV GSVGILAFFF FTHRIRIVQD TAPPLNYYWV PILTVIVGSY LIAHGFFSVY 660
GMCVDTLFLC FLEDLERNDG SAERPYFMSS TLKKLLNKTN KKAAES 706 |
Gene Ontology | GO:0016021; C:integral to membrane; TAS:UniProtKB. GO:0005886; C:plasma membrane; TAS:Reactome. GO:0015220; F:choline transmembrane transporter activity; TAS:UniProtKB. GO:0004871; F:signal transducer activity; IMP:UniProtKB. GO:0006656; P:phosphatidylcholine biosynthetic process; TAS:Reactome. GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IMP:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |