| Tag | Content |
|---|
| CPLM ID | CPLM-010448 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP-dependent Clp protease proteolytic subunit |
Protein Synonyms/Alias | Caseinolytic protease; Endopeptidase Clp; Stress protein G7 |
Gene Name | clpP |
Gene Synonyms/Alias | yvdN; BSU34540 |
Created Date | July 27, 2013 |
Organism | Bacillus subtilis (strain 168) |
NCBI Taxa ID | 224308 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 196 | ILTHTEDKK****** | acetylation | [1] |
|
Reference | [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis. Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG. Proteomics. 2013 May;13(10-11):1726-36. [ PMID: 23468065] |
Functional Description | Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins (By similarity). ClpXP is involved in the complete degradation of the Site-2 clipped anti-sigma-W factor RsiW. This results in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor. |
Sequence Annotation | ACT_SITE 98 98 By similarity.
ACT_SITE 123 123 By similarity. |
Keyword | 3D-structure; ATP-binding; Complete proteome; Cytoplasm; Direct protein sequencing; Hydrolase; Nucleotide-binding; Protease; Reference proteome; Serine protease; Stress response. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 197 AA |
Protein Sequence | MNLIPTVIEQ TNRGERAYDI YSRLLKDRII MLGSAIDDNV ANSIVSQLLF LAAEDPEKEI 60
SLYINSPGGS ITAGMAIYDT MQFIKPKVST ICIGMAASMG AFLLAAGEKG KRYALPNSEV 120
MIHQPLGGAQ GQATEIEIAA KRILLLRDKL NKVLAERTGQ PLEVIERDTD RDNFKSAEEA 180
LEYGLIDKIL THTEDKK 197 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |