CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-006605
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 DNA-directed RNA polymerase III subunit RPC5 
Protein Synonyms/Alias
 RNA polymerase III subunit C5; DNA-directed RNA polymerase III 37 kDa polypeptide; RNA polymerase III subunit C37 
Gene Name
 RPC37 
Gene Synonyms/Alias
 YKR025W 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
217QVVTMSVKSVNDPSQubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific peripheric component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. The RPC53/RPC4-RPC37/RPC5 subcomplex is required for terminator recognition and reinitiation. 
Sequence Annotation
 MOD_RES 61 61 Phosphothreonine.  
Keyword
 Complete proteome; DNA-directed RNA polymerase; Nucleus; Phosphoprotein; Reference proteome; Transcription. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 282 AA 
Protein Sequence
MSIDNKLFVT EEDEEDRTQD RADVEDESND IDMIADENGT NSAIANEQEE KSEEVKAEDD 60
TGEEEEDDPV IEEFPLKISG EEESLHVFQY ANRPRLVGRK PAEHPFISAA RYKPKSHLWE 120
IDIPLDEQAF YNKDKAESEW NGVNVQTLKG VGVENNGQYA AFVKDMQVYL VPIERVAQLK 180
PFFKYIDDAN VTRKQEDARR NPNPSSQRAQ VVTMSVKSVN DPSQNRLTGS LLAHKVADEE 240
ANIELTWAEG TFEQFKDTIV KEAEDKTLVA LEKQEDYIDN LV 282 
Gene Ontology
 GO:0005666; C:DNA-directed RNA polymerase III complex; IDA:SGD.
 GO:0003899; F:DNA-directed RNA polymerase activity; IEA:UniProtKB-KW.
 GO:0042797; P:tRNA transcription from RNA polymerase III promoter; IDA:SGD. 
Interpro
 IPR006886; RNA_pol_III_Rpc5. 
Pfam
 PF04801; Sin_N 
SMART
  
PROSITE
  
PRINTS