CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-031539
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Regulation of nuclear pre-mRNA domain-containing protein 2 
Protein Synonyms/Alias
 cDNA FLJ54323 
Gene Name
 RPRD2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
125KSVERIFKIWEDRNVubiquitination[1]
267KVVANAYKTFANRVNubiquitination[2]
363KIIVEDRKEKPAEKSubiquitination[3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 934 AA 
Protein Sequence
MAAGGGGGSS KASSSSASSA GALESSLDRK FQSVTNTMES IQGLSSWCIE NKKHHSTIVY 60
HWMKWLRRSA YPHRLNLFYL ANDVIQNCKR KNAIIFRESF ADVLPEAAAL VKDPSVSKSV 120
ERIFKIWEDR NVYPEEMIVA LREALTSTNP KAALKSKIVA EFRSQALIEE LLLYKRSEDQ 180
IELKEKQLST MRVDVCSTET LKCLKDKTGG KKFSKEFEEA SSKLEEFVNG LDKQVKNGPS 240
LTEALENAGI FYEAQYKEVK VVANAYKTFA NRVNNLKKKL DQLKSTLPDP EESPVPSPSM 300
DAPSPTGSES PFQGMGGEES QSPTMESEKS ATPEPVTDNR DVEDMELSDV EDDGSKIIVE 360
DRKEKPAEKS AVSTSVPTKP TENISKASSC TPVPVTMTAT PPLPKPVNTS LSPSPALALP 420
NLANVDLAKI SSILSSLTSV MKNTGVSPAS RPSPGTPTSP SNLTSGLKTP APATTTSHNP 480
LANILSKVEI TPESILSALS KTQTQSAPAL QGLSSLLQSV TGNPVPASEA ASQSTSASPA 540
NTTVSTIKGR NLPSSAQPFI PKSFNYSPNS STSEVSSTSA SKASIGQSPG LPSTTFKLPS 600
NSLGFTATHN TSPAAPPTEV TICQSSEVSK PKLESESTSP SLEMKIHNFL KGNPGFSGLN 660
LNIPILSSLG SSAPSESHPS DFQRGPTSTS IDNIDGTPVR DERSGTPTQD EMMDKPTSSS 720
VDTMSLLSKI ISPGSSTPSS TRSPPPGRDE SYPRELSNSV STYRPFGLGS ESPYKQPSDG 780
MERPSSLMDS SQEKFYPDTS FQEDEDYRDF EYSGPPPSAM MNLEKKPAKS ILKSSKLSDT 840
TEYQPILSSY SHRAQEFGVK SAFPPSVRAL LDSSENCDRL SSSPGLFGAF SVRGNEPGSD 900
RSPSPKHPCR SHGSPTHVRR GESPGLHHFH HVDD 934 
Gene Ontology
  
Interpro
 IPR006569; CID_dom.
 IPR008942; ENTH_VHS.
 IPR006903; RNA_pol_II-bd. 
Pfam
 PF04818; CTD_bind 
SMART
 SM00582; RPR 
PROSITE
 PS51391; CID 
PRINTS