UniProt Accession

 TDCF_ECOLI; P0AGL2; P42631; Q2M995 

Genbank Protein ID

 U18997; U00096; AP009048 

Genbank Nucleotide ID

 AAA57917.1; AAC76148.2; BAE77161.1 

Protein Name

 Putative reactive intermediate deaminase TdcF 

Protein Synonyms/Alias

  

Gene Name

 tdcF 

Gene Synonyms/Alias

 yhaR; b3113; JW5521 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
115	VQVARLPKDVKLEIE	acetylation	[1]
118	ARLPKDVKLEIEAIA	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 May be a post-translational regulator that controls the metabolic fate of L-threonine or the potentially toxic intermediate 2-ketobutyrate. 

Sequence Annotation

 REGION 105 107 Substrate binding.
 BINDING 120 120 Substrate.
 MOD_RES 58 58 N6-(pyridoxal phosphate)lysine (By  

Keyword

 3D-structure; Complete proteome; Hydrolase; Pyridoxal phosphate; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 129 AA 

Protein Sequence

Gene Ontology

 GO:0019239; F:deaminase activity; IEA:InterPro.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0042802; F:identical protein binding; IDA:EcoCyc.
 GO:0070689; P:L-threonine catabolic process to propionate; IEA:UniProtKB-UniPathway.
 GO:0006566; P:threonine metabolic process; IDA:UniProtKB. 

Interpro

 IPR013813; Endoribo_LPSP/chorism_mut-like.
 IPR006056; YjgF-like.
 IPR019897; YjgF-like_CS.
 IPR006175; YjgF/Yer057p/UK114. 

Pfam

 PF01042; Ribonuc_L-PSP 

SMART

  

PROSITE

 PS01094; UPF0076 

PRINTS