| Tag | Content |
|---|
| CPLM ID | CPLM-013522 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Copper-exporting P-type ATPase A |
Protein Synonyms/Alias | |
Gene Name | copA |
Gene Synonyms/Alias | ybaR; b0484; JW0473 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 19 | LSCGHCVKRVKESLE | acetylation | [1] | | 169 | EAIEDDAKRRERQQE | acetylation | [1] | | 316 | RSSKALEKLLDLTPP | acetylation | [1] | | 334 | LVTDEGEKSVPLAEV | acetylation | [1] | | 539 | KPQVVAVKTFADVDE | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Involved in copper export. May also be involved in silver export. |
Sequence Annotation | DOMAIN 4 65 HMA 1.
DOMAIN 100 163 HMA 2.
ACT_SITE 523 523 4-aspartylphosphate intermediate
METAL 14 14 Copper (Potential).
METAL 17 17 Copper (Potential).
METAL 110 110 Copper (Potential).
METAL 113 113 Copper (Potential).
METAL 720 720 Magnesium (By similarity).
METAL 724 724 Magnesium (By similarity). |
Keyword | ATP-binding; Cell membrane; Complete proteome; Copper; Copper transport; Direct protein sequencing; Hydrolase; Ion transport; Magnesium; Membrane; Metal-binding; Nucleotide-binding; Phosphoprotein; Reference proteome; Repeat; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 834 AA |
Protein Sequence | MSQTIDLTLD GLSCGHCVKR VKESLEQRPD VEQADVSITE AHVTGTASAE QLIETIKQAG 60
YDASVSHPKA KPLAESSIPS EALTAVSEAL PAATADDDDS QQLLLSGMSC ASCVTRVQNA 120
LQSVPGVTQA RVNLAERTAL VMGSASPQDL VQAVEKAGYG AEAIEDDAKR RERQQETAVA 180
TMKRFRWQAI VALAVGIPVM VWGMIGDNMM VTADNRSLWL VIGLITLAVM VFAGGHFYRS 240
AWKSLLNGAA TMDTLVALGT GVAWLYSMSV NLWPQWFPME ARHLYYEASA MIIGLINLGH 300
MLEARARQRS SKALEKLLDL TPPTARLVTD EGEKSVPLAE VQPGMLLRLT TGDRVPVDGE 360
ITQGEAWLDE AMLTGEPIPQ QKGEGDSVHA GTVVQDGSVL FRASAVGSHT TLSRIIRMVR 420
QAQSSKPEIG QLADKISAVF VPVVVVIALV SAAIWYFFGP APQIVYTLVI ATTVLIIACP 480
CALGLATPMS IISGVGRAAE FGVLVRDADA LQRASTLDTV VFDKTGTLTE GKPQVVAVKT 540
FADVDEAQAL RLAAALEQGS SHPLARAILD KAGDMQLPQV NGFRTLRGLG VSGEAEGHAL 600
LLGNQALLNE QQVGTKAIEA EITAQASQGA TPVLLAVDGK AVALLAVRDP LRSDSVAALQ 660
RLHKAGYRLV MLTGDNPTTA NAIAKEAGID EVIAGVLPDG KAEAIKHLQS EGRQVAMVGD 720
GINDAPALAQ ADVGIAMGGG SDVAIETAAI TLMRHSLMGV ADALAISRAT LHNMKQNLLG 780
AFIYNSIGIP VAAGILWPFT GTLLNPVVAG AAMALSSITV VSNANRLLRF KPKE 834 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0031224; C:intrinsic to membrane; IDA:EcoliWiki. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0015662; F:ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism; IDA:EcoliWiki. GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0006825; P:copper ion transport; IMP:EcoliWiki. GO:0010273; P:detoxification of copper ion; IMP:EcoliWiki. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |