UniProt Accession

 Q94883_DROME; Q94883 

Genbank Protein ID

 AE014134; BT099709; AE014134; AB010823 

Genbank Nucleotide ID

 AAF52841.1; ACV53073.1; AGB92846.1; BAA24827.1 

Protein Name

 DNA replication-related element factor, isoform A 

Protein Synonyms/Alias

 DNA replication-related element factor, isoform B; DREF; FI03642p 

Gene Name

 Dref 

Gene Synonyms/Alias

 Dref-RA; Dmel_CG5838 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
189	ERLVMEPKYGRKRKV	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 709 AA 

Protein Sequence

Gene Ontology

 GO:0005700; C:polytene chromosome; IDA:FlyBase.
 GO:0005667; C:transcription factor complex; IPI:FlyBase.
 GO:0005509; F:calcium ion binding; ISS:UniProtKB.
 GO:0003700; F:sequence-specific DNA binding transcription factor activity; TAS:FlyBase.
 GO:0000976; F:transcription regulatory region sequence-specific DNA binding; IDA:FlyBase.
 GO:0022416; P:chaeta development; IMP:FlyBase.
 GO:0001745; P:compound eye morphogenesis; IMP:FlyBase.
 GO:0042023; P:DNA endoreduplication; IMP:FlyBase.
 GO:0006264; P:mitochondrial DNA replication; TAS:FlyBase.
 GO:0007052; P:mitotic spindle organization; IMP:FlyBase.
 GO:0022008; P:neurogenesis; IMP:FlyBase.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:FlyBase.
 GO:0046777; P:protein autophosphorylation; ISS:UniProtKB.
 GO:0042981; P:regulation of apoptotic process; IDA:FlyBase.
 GO:0051726; P:regulation of cell cycle; NAS:FlyBase.
 GO:2000495; P:regulation of cell proliferation involved in compound eye morphogenesis; IDA:FlyBase.
 GO:2000278; P:regulation of DNA biosynthetic process; IDA:FlyBase.
 GO:0006357; P:regulation of transcription from RNA polymerase II promoter; IMP:FlyBase.
 GO:0051123; P:RNA polymerase II transcriptional preinitiation complex assembly; IPI:GOC.
 GO:0045035; P:sensory organ precursor cell division; IMP:FlyBase. 

Interpro

 IPR012337; RNaseH-like_dom.
 IPR003656; Znf_BED_prd. 

Pfam

 PF02892; zf-BED 

SMART

 SM00614; ZnF_BED 

PROSITE

 PS50808; ZF_BED 

PRINTS