CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018096
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 526 
Protein Synonyms/Alias
  
Gene Name
 ZNF526 
Gene Synonyms/Alias
 KIAA1951 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
570PITGLYNKSPYYCGTubiquitination[1, 2]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
 May be involved in transcriptional regulation (By similarity). 
Sequence Annotation
 ZN_FING 57 79 C2H2-type 1.
 ZN_FING 108 130 C2H2-type 2.
 ZN_FING 140 163 C2H2-type 3.
 ZN_FING 197 219 C2H2-type 4.
 ZN_FING 305 327 C2H2-type 5.
 ZN_FING 332 354 C2H2-type 6.
 ZN_FING 360 382 C2H2-type 7.
 ZN_FING 388 409 C2H2-type 8.
 ZN_FING 442 465 C2H2-type 9.
 ZN_FING 472 494 C2H2-type 10.
 ZN_FING 500 522 C2H2-type 11.
 ZN_FING 528 550 C2H2-type 12.
 ZN_FING 573 595 C2H2-type 13.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 670 AA 
Protein Sequence
MAEVVAEVAE MPTQMSPGAV EMSTPMSAEM MEMSTEVTEM TPGEALASSL FFQHHQFMCS 60
ECGSLYNTLE EVLSHQEQHM LAVSEEEALT TQNVGLEPEL VPGAEGPFQC GECSQLILSP 120
GELLAHQDAH LRESANQIQY QCWDCQELFP SPELWVAHRK AQHLSATVAE PPVPPPLPPP 180
TPLPPPSPPS EVKMEPYECP ECSTLCATPE EFLEHQGTHF DSLEKEERNG LEEEEEDDEE 240
DEEDDEEMED EEAMAEVGDD AVGGDESTAG WAQGCGDCPQ HQPSAGARRQ HRRTAHSPAS 300
ATHPFHCSQC QRSFSSANRL QAHGRAHVGG THECTTCSKV FKKAASLEQH LRLHRGEARY 360
LCVDCGRGFG TELTLVAHRR AHTANPLHRC RCGKTFSNMT KFLYHRRTHA GKSGAPPTGA 420
TAPPAPAEPT PPPPPPAPPA QLPCPQCSKS FASASRLSRH RRAVHGPPER RHRCGVCGKG 480
FKKLIHVRNH LRTHTGERPF QCHSCGKTFA SLANLSRHQL THTGARPYQC LDCGKRFTQS 540
SNLQQHRRLH LRPVAFARAP RLPITGLYNK SPYYCGTCGR WFRAMAGLRL HQRVHARART 600
LTLQPPRSPS PAPPPPPEPQ QTIMCTELGE TIAIIETSQP LALEDTLQLC QAALGASEAG 660
GLLQLDTAFV 670 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF00096; zf-C2H2 
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS