| Tag | Content |
|---|
| CPLM ID | CPLM-015711 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ell-associated factor Eaf |
Protein Synonyms/Alias | dEaf |
Gene Name | Eaf |
Gene Synonyms/Alias | CG11166 |
Created Date | July 27, 2013 |
Organism | Drosophila melanogaster (Fruit fly) |
NCBI Taxa ID | 7227 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 190 | RNNIIDFKPRNSPMQ | acetylation | [1] |
|
Reference | [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation. Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C. Sci Signal. 2011 Jul 26;4(183):ra48. [ PMID: 21791702] |
Functional Description | Promotes transcriptional elongation by Su(Tpl)/ELL. Essential for development. |
Sequence Annotation | MOD_RES 194 194 Phosphoserine. |
Keyword | Activator; Alternative splicing; Complete proteome; Developmental protein; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 504 AA |
Protein Sequence | MMMTKQKNSL AERLNIGEEV RELKLGATFN PKNTSTAFHT IKYDFKPASV DTSRMASVDV 60
GSNNQVTVTV PNSESSGVPH TVYKGNQREY AKECLMIYDK ETGAITIEKL NHNIQVKKTR 120
NEVTNKSVQL PGQNMGQPHN QGANGAAPVA VPVPGQGSGT APKMENSTMR ISTKTKVSTG 180
SRRNNIIDFK PRNSPMQQNS PSRPVPVHRS PQSAPAWDAN NAQQTLPSIP LITDDDDFGL 240
RAALHNSGHG NTSGTAAGQP DFGSTSSSTH IGKQRQAPPH GHGKRQQMHQ RLSPPMAQQQ 300
QPSNYGRGYN GGHNHAQQQQ HHQRNSPQQQ RPSAYGHGNS MPIDVDSSRE HELTSQSVAQ 360
AAAALEQQIG GALSASSSSS ESDSSDSDSG SDSDDSTEDD RSTQGQQQDH QQQQQQQHQV 420
YQNHKHTQQQ VAQQHHNQLP NLGLGSISPA YGSSHQQQHQ QQMLPHQQKQ KQQSGIYASN 480
GGFPNDFLQN DLQLSSNSSD DDDD 504 |
Gene Ontology | GO:0032783; C:ELL-EAF complex; IPI:FlyBase. GO:0007275; P:multicellular organismal development; IEA:UniProtKB-KW. GO:0045893; P:positive regulation of transcription, DNA-dependent; IMP:UniProtKB. GO:0043620; P:regulation of DNA-dependent transcription in response to stress; IMP:FlyBase. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. GO:0042060; P:wound healing; IMP:FlyBase. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |