CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021880
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome P450 3A41 
Protein Synonyms/Alias
  
Gene Name
 Cyp3a41a; Cyp3a41b 
Gene Synonyms/Alias
 Cyp3a41 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
96MIKNVLVKECFSVFTubiquitination[1]
143TFTSGKLKEMFPVIEubiquitination[1]
250KDSIEFFKKFVNRMKubiquitination[1]
380RLERFCKKDVELNGVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 METAL 443 443 Iron (heme axial ligand) (By similarity).  
Keyword
 Complete proteome; Endoplasmic reticulum; Heme; Iron; Membrane; Metal-binding; Microsome; Monooxygenase; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 504 AA 
Protein Sequence
MNLFSALSLD TWVLLAIILV LLYRYGTRTH GLFKKQGIPG PKPLPFLGTV LNYYKGLWKF 60
DMECYEKYGK TWGLFDGQMP LFVITDPEMI KNVLVKECFS VFTNRREFGP VGIMSKAISI 120
SKDEEWKRYR ALLSPTFTSG KLKEMFPVIE QYGDILVKYL MQEAEKGKPV TMKDVLGAYS 180
IDVITSTSFG VNVDSLNNPE DPFVEKAKGI LRVDFFDPLV FSVVLFPFLT PVYEMLNICM 240
FPKDSIEFFK KFVNRMKESR LDSKQKHRVD FLQLMMNAHN NSKDKDSHKA LSDMEITAQS 300
IVFIFAGYET TSSTLSFTLY CLATHPDIQK KLQEEIDETL PNKAPPTYDT VMEMEYLDMV 360
LNETLRLYPI GNRLERFCKK DVELNGVYIP KGSTVMIPSY ALHHDPQHWP EPEEFQPERF 420
SKENKGSIDP YLYMPFGIGP RNCIGMRFAF MTMKLALTKV MQNFSFQPCQ ETQIPLKLSR 480
QGLLQPEKPI VLKVVPRDVV ITGA 504 
Gene Ontology
 GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell.
 GO:0070330; F:aromatase activity; IEA:EC.
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR008072; Cyt_P450_E_CYP3A.
 IPR002402; Cyt_P450_E_grp-II. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00464; EP450II.
 PR01689; EP450IICYP3A.
 PR00385; P450.