| Tag | Content |
|---|
| CPLM ID | CPLM-010756 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein phosphatase PP2A regulatory subunit B |
Protein Synonyms/Alias | Cell division control protein 55; PR55 |
Gene Name | CDC55 |
Gene Synonyms/Alias | YGL190C; G1345 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 136 | TEGVTFAKKGKPDNH | acetylation | [1] | | 160 | VLSLQSLKLPQLSQH | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | Phosphatase 2A affects a variety of biological processes in the cell such as transcription, cell cycle progression and cellular morphogenesis, and provides an initial identification of critical substrates for this phosphatase. The regulatory subunit may direct the catalytic subunit to distinct, albeit overlapping, subsets of substrates. |
Sequence Annotation | REPEAT 23 62 WD 1.
REPEAT 82 123 WD 2.
REPEAT 182 220 WD 3.
REPEAT 231 271 WD 4.
REPEAT 290 328 WD 5.
REPEAT 345 386 WD 6.
REPEAT 495 525 WD 7.
MOD_RES 124 124 Phosphoserine. |
Keyword | Cell cycle; Complete proteome; Phosphoprotein; Reference proteome; Repeat; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 526 AA |
Protein Sequence | MAQNNFDFKF SQCFGDKADI VVTEADLITA VEFDYTGNYL ATGDKGGRVV LFERSNSRHC 60
EYKFLTEFQS HDAEFDYLKS LEIEEKINEI KWLRPTQRSH FLLSTNDKTI KLWKVYEKNI 120
KLVSQNNLTE GVTFAKKGKP DNHNSRGGSV RAVLSLQSLK LPQLSQHDKI IAATPKRIYS 180
NAHTYHINSI SLNSDQETFL SADDLRINLW NLDIPDQSFN IVDIKPTNME ELTEVITSAE 240
FHPQECNLFM YSSSKGTIKL CDMRQNSLCD NKTKTFEEYL DPINHNFFTE ITSSISDIKF 300
SPNGRYIASR DYLTVKIWDV NMDNKPLKTI NIHEQLKERL SDTYENDAIF DKFEVNFSGD 360
SSSVMTGSYN NNFMIYPNVV TSGDNDNGIV KTFDEHNAPN SNSNKNIHNS IQNKDSSSSG 420
NSHKRRSNGR NTGMVGSSNS SRSSIAGGEG ANSEDSGTEM NEIVLQADKT AFRNKRYGSL 480
AQRSARNKDW GDDIDFKKNI LHFSWHPREN SIAVAATNNL FIFSAL 526 |
Gene Ontology | GO:0005935; C:cellular bud neck; IDA:SGD. GO:0005934; C:cellular bud tip; IDA:SGD. GO:0005737; C:cytoplasm; IDA:SGD. GO:0005634; C:nucleus; IDA:SGD. GO:0000159; C:protein phosphatase type 2A complex; IEA:InterPro. GO:0008601; F:protein phosphatase type 2A regulator activity; IPI:SGD. GO:0007049; P:cell cycle; IEA:UniProtKB-KW. GO:0000078; P:cell shape checkpoint; IGI:SGD. GO:0001100; P:negative regulation of exit from mitosis; IMP:SGD. GO:0010971; P:positive regulation of G2/M transition of mitotic cell cycle; IMP:SGD. GO:0006470; P:protein dephosphorylation; TAS:SGD. GO:0007165; P:signal transduction; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |