UniProt Accession

 THUM1_MOUSE; Q99J36; Q3U6Y3 

Genbank Protein ID

 AK032078; AK152912; BC004776 

Genbank Nucleotide ID

 BAC27685.1; BAE31591.1; AAH04776.1 

Protein Name

 THUMP domain-containing protein 1 

Protein Synonyms/Alias

  

Gene Name

 Thumpd1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
150	HILQDMYKTKKKKTR	ubiquitination	[1]
261	KDYVLFRKYNLQEVV	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

 DOMAIN 147 254 THUMP.
 MOD_RES 2 2 N-acetylalanine (By similarity).
 MOD_RES 8 8 Phosphoserine.
 MOD_RES 86 86 Phosphoserine.
 MOD_RES 88 88 Phosphoserine.  

Keyword

 Acetylation; Complete proteome; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 350 AA 

Protein Sequence

Gene Ontology

 GO:0003723; F:RNA binding; IEA:InterPro. 

Interpro

 IPR004114; THUMP. 

Pfam

 PF02926; THUMP 

SMART

 SM00981; THUMP 

PROSITE

 PS51165; THUMP 

PRINTS