CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021396
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 768 
Protein Synonyms/Alias
  
Gene Name
 ZNF768 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
157ESQNTELKTQSPEFEubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 ZN_FING 261 283 C2H2-type 1.
 ZN_FING 289 311 C2H2-type 2.
 ZN_FING 317 339 C2H2-type 3.
 ZN_FING 345 367 C2H2-type 4.
 ZN_FING 373 395 C2H2-type 5.
 ZN_FING 401 423 C2H2-type 6.
 ZN_FING 429 451 C2H2-type 7.
 ZN_FING 457 479 C2H2-type 8.
 ZN_FING 485 507 C2H2-type 9.
 ZN_FING 513 535 C2H2-type 10.
 MOD_RES 17 17 Phosphoserine.
 MOD_RES 83 83 Phosphoserine.
 MOD_RES 90 90 Phosphoserine.
 MOD_RES 97 97 Phosphoserine.
 MOD_RES 160 160 Phosphoserine.  
Keyword
 Complete proteome; DNA-binding; Metal-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 540 AA 
Protein Sequence
MEREALPWGL EPQDVQSSDE MRSPEGYLRG NMSENEEEEI SQQEGSGDYE VEEIPFGLEP 60
QSPGFEPQSP EFEPQSPRFE PESPGFESRS PGLVPPSPEF APRSPESDSQ SPEFESQSPR 120
YEPQSPGYEP RSPGYEPRSP GYESESSRYE SQNTELKTQS PEFEAQSSKF QEGAEMLLNP 180
EEKSPLNISV GVHPLDSFTQ GFGEQPTGDL PIGPPFEMPT GALLSTPQFE MLQNPLGLTG 240
ALRGPGRRGG RARGGQGPRP NICGICGKSF GRGSTLIQHQ RIHTGEKPYK CEVCSKAFSQ 300
SSDLIKHQRT HTGERPYKCP RCGKAFADSS YLLRHQRTHS GQKPYKCPHC GKAFGDSSYL 360
LRHQRTHSHE RPYSCTECGK CYSQNSSLRS HQRVHTGQRP FSCGICGKSF SQRSALIPHA 420
RSHAREKPFK CPECGKRFGQ SSVLAIHART HLPGRTYSCP DCGKTFNRSS TLIQHQRSHT 480
GERPYRCAVC GKGFCRSSTL LQHHRVHSGE RPYKCDDCGK AFSQSSDLIR HQRTHAAGRR 540 
Gene Ontology
 GO:0005665; C:DNA-directed RNA polymerase II, core complex; IEA:InterPro.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006366; P:transcription from RNA polymerase II promoter; IEA:InterPro. 
Interpro
 IPR000684; RNA_pol_II_repeat_euk.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF05001; RNA_pol_Rpb1_R
 PF00096; zf-C2H2 
SMART
 SM00355; ZnF_C2H2 
PROSITE
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS