UniProt Accession

 BZW1_PONAB; Q5R7L4 

Genbank Protein ID

 CR860101 

Genbank Nucleotide ID

 CAH92246.1 

Protein Name

 Basic leucine zipper and W2 domain-containing protein 1 

Protein Synonyms/Alias

  

Gene Name

 BZW1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Pongo abelii (Sumatran orangutan) (Pongo pygmaeus abelii) 

NCBI Taxa ID

 9601 

Lysine Modification

Position	Peptide	Type	References
5	***MNNQKQQKPTLS	ubiquitination	[1]
60	FLDASGAKLDYRRYA	ubiquitination	[2]
231	QSVEHFTKYFTEAGL	ubiquitination	[2]
239	YFTEAGLKELSEYVR	ubiquitination	[2]
255	QQTIGARKELQKELQ	ubiquitination	[1, 2]
272	MSRGDPFKDIILYVK	ubiquitination	[2]

Reference

 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965] 

Functional Description

 Enhances histone H4 gene transcription but does not seem to bind DNA directly (By similarity). 

Sequence Annotation

 DOMAIN 247 414 W2.
 MOD_RES 411 411 Phosphoserine (By similarity).
 MOD_RES 413 413 Phosphoserine (By similarity).  

Keyword

 Activator; Complete proteome; Phosphoprotein; Reference proteome; Transcription; Transcription regulation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 419 AA 

Protein Sequence

Gene Ontology

 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 

Interpro

 IPR016024; ARM-type_fold.
 IPR016021; MIF4-like_typ_1/2/3.
 IPR003307; W2_domain. 

Pfam

 PF02020; W2 

SMART

 SM00515; eIF5C 

PROSITE

 PS51363; W2 

PRINTS