CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004972
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L3 
Protein Synonyms/Alias
 L4 
Gene Name
 Rpl3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
39FPKDDPSKPVHLTAFacetylation[1]
154EKDFNSMKKYCQVIRacetylation[1]
286EINKKIYKIGQGYLIubiquitination[2]
300IKDGKLIKNNASTDYubiquitination[2]
373KFIDTTSKFGHGRFQacetylation[1]
385RFQTMEEKKAFMGPLacetylation[1]
399LKKDRIAKEEGA***acetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis.
 Na CH, Jones DR, Yang Y, Wang X, Xu Y, Peng J.
 J Proteome Res. 2012 Sep 7;11(9):4722-32. [PMID: 22871113] 
Functional Description
 The L3 protein is a component of the large subunit of cytoplasmic ribosomes. 
Sequence Annotation
 MOD_RES 13 13 Phosphoserine (By similarity).
 MOD_RES 294 294 N6-acetyllysine (By similarity).
 MOD_RES 304 304 Phosphoserine (By similarity).
 MOD_RES 366 366 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Complete proteome; Cytoplasm; Direct protein sequencing; Nucleus; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 403 AA 
Protein Sequence
MSHRKFSAPR HGSLGFLPRK RSSRHRGKVK SFPKDDPSKP VHLTAFLGYK AGMTHIVREV 60
DRPGSKVNKK EVVEAVTIVE TPPMVVVGIV GYVETPRGLR TFKTVFAEHI SDECKRRFYK 120
NWHKSKKKAF TKYCKKWQDD TGKKQLEKDF NSMKKYCQVI RIIAHTQMRL LPLRQKKAHL 180
MEIQVNGGTV AEKLDWARER LEQQVPVNQV FGQDEMIDVI GVTKGKGYKG VTSRWHTKKL 240
PRKTHRGLRK VACIGAWHPA RVAFSVARAG QKGYHHRTEI NKKIYKIGQG YLIKDGKLIK 300
NNASTDYDLS DKSINPLGGF VHYGEVTNDF IMLKGCVVGT KKRVLTLRKS LLVQTKRRAL 360
EKIDLKFIDT TSKFGHGRFQ TMEEKKAFMG PLKKDRIAKE EGA 403 
Gene Ontology
 GO:0005730; C:nucleolus; ISS:UniProtKB.
 GO:0005840; C:ribosome; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR000597; Ribosomal_L3.
 IPR019926; Ribosomal_L3_CS.
 IPR009000; Transl_elong_init/rib_B-barrel. 
Pfam
 PF00297; Ribosomal_L3 
SMART
  
PROSITE
 PS00474; RIBOSOMAL_L3 
PRINTS