CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-011819
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ubiquitin-like protein SMT3 
Protein Synonyms/Alias
  
Gene Name
 SMT3 
Gene Synonyms/Alias
 YDR510W; D9719.15 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
11SEVNQEAKPEVKPEVsumoylation[1]
15QEAKPEVKPEVKPETsumoylation[1]
19PEVKPEVKPETHINLsumoylation[1]
38GSSEIFFKIKKTTPLacetylation[2]
54RLMEAFAKRQGKEMDacetylation[2]
54RLMEAFAKRQGKEMDubiquitination[3]
58AFAKRQGKEMDSLRFacetylation[2]
Reference
 [1] Activation of the Slx5-Slx8 ubiquitin ligase by poly-small ubiquitin-like modifier conjugates.
 Mullen JR, Brill SJ.
 J Biol Chem. 2008 Jul 18;283(29):19912-21. [PMID: 18499666]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919]
 [3] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301
Functional Description
 Not known; suppressor of MIF2 mutations. 
Sequence Annotation
 DOMAIN 22 98 Ubiquitin-like.
 MOD_RES 2 2 N-acetylserine.
 CROSSLNK 98 98 Glycyl lysine isopeptide (Gly-Lys)  
Keyword
 3D-structure; Acetylation; Complete proteome; Isopeptide bond; Reference proteome; Ubl conjugation pathway. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 101 AA 
Protein Sequence
MSDSEVNQEA KPEVKPEVKP ETHINLKVSD GSSEIFFKIK KTTPLRRLME AFAKRQGKEM 60
DSLRFLYDGI RIQADQTPED LDMEDNDIIE AHREQIGGAT Y 101 
Gene Ontology
 GO:0000794; C:condensed nuclear chromosome; IDA:SGD.
 GO:0005940; C:septin ring; IDA:SGD.
 GO:0031386; F:protein tag; IDA:SGD.
 GO:0016925; P:protein sumoylation; IDA:SGD. 
Interpro
 IPR000626; Ubiquitin.
 IPR019955; Ubiquitin_supergroup. 
Pfam
 PF00240; ubiquitin 
SMART
 SM00213; UBQ 
PROSITE
 PS50053; UBIQUITIN_2 
PRINTS