CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-012202
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ADP-ribosylation factor-related protein 1 
Protein Synonyms/Alias
 ARF-related protein 1; ARP 
Gene Name
 ARFRP1 
Gene Synonyms/Alias
 ARP1 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
112EERLAESKQAFEKVVubiquitination[1]
174ACSALTGKGVREGIEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
 Possibly involved in plasma membrane-related signaling events. 
Sequence Annotation
 NP_BIND 24 31 GTP (By similarity).
 NP_BIND 75 79 GTP (By similarity).
 NP_BIND 134 137 GTP (By similarity).  
Keyword
 Alternative splicing; Complete proteome; Golgi apparatus; GTP-binding; Nucleotide-binding; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 201 AA 
Protein Sequence
MYTLLSGLYK YMFQKDEYCI LILGLDNAGK TTFLEQSKTR FNKNYKGMSL SKITTTVGLN 60
IGTVDVGKAR LMFWDLGGQE ELQSLWDKYY AECHGVIYVI DSTDEERLAE SKQAFEKVVT 120
SEALCGVPVL VLANKQDVET CLSIPDIKTA FSDCTSKIGR RDCLTQACSA LTGKGVREGI 180
EWMVKCVVRN VHRPPRQRDI T 201 
Gene Ontology
 GO:0005794; C:Golgi apparatus; IDA:UniProtKB.
 GO:0016020; C:membrane; TAS:ProtInc.
 GO:0005802; C:trans-Golgi network; IDA:UniProtKB.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; TAS:ProtInc.
 GO:0007369; P:gastrulation; IEA:Compara.
 GO:0043001; P:Golgi to plasma membrane protein transport; IMP:UniProtKB.
 GO:0034067; P:protein localization to Golgi apparatus; IMP:UniProtKB.
 GO:0042147; P:retrograde transport, endosome to Golgi; IMP:UniProtKB.
 GO:0007165; P:signal transduction; TAS:ProtInc.
 GO:0007264; P:small GTPase mediated signal transduction; IEA:InterPro. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR024156; Small_GTPase_ARF.
 IPR006689; Small_GTPase_ARF/SAR. 
Pfam
 PF00025; Arf 
SMART
 SM00177; ARF 
PROSITE
 PS51417; ARF 
PRINTS
 PR00449; RASTRNSFRMNG.