CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027350
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Tat-binding protein homolog 
Protein Synonyms/Alias
  
Gene Name
 PFL2345c 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Plasmodium falciparum (isolate 3D7) 
NCBI Taxa ID
 36329 
Lysine Modification
Position
Peptide
Type
References
252SGSELVQKYIGEGSRacetylation[1]
Reference
 [1] Extensive lysine acetylation occurs in evolutionarily conserved metabolic pathways and parasite-specific functions during Plasmodium falciparum intraerythrocytic development.
 Miao J, Lawrence M, Jeffers V, Zhao F, Parker D, Ge Y, Sullivan WJ Jr, Cui L.
 Mol Microbiol. 2013 Aug;89(4):660-75. [PMID: 23796209] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 435 AA 
Protein Sequence
MAAVDFDVRS KNLSEGIKNE ISEKNMENNN NNDNNKNSSA LNEEQVQSGI KRYYELKIEE 60
YESIINKKLQ NKKRLEAQRN ELNARVRELC DEIQYLLEAA SYVGEIVKPM GKNKVLVKIN 120
PEGKYVVDIA RHINISHCTP NTRVALYNDS YKLHKILPSK VDPLVSLMKV EKVPDSTYEM 180
VGGLDQQVKE VKEVIELPVK HPEIFESLGI SQPKGVLLYG PPGTGKTLLA RAVAHHTDCT 240
FIRVSGSELV QKYIGEGSRM VRELFVMARE HAPSIIFMDE IDSIGSQRIE GEHGDSEVQR 300
TMMELLNQLD GFESTQNIKV IMCTNRIDIL DEALLRPGRI DRKIEFPNPN VEARMEILKI 360
HSRKMNLMRG IDMLKIATDM NNCSGAEVKA VCTEAGMFAL RERRVHVTQE DFEMAVAKVM 420
KQDAEKNFTL RKLWK 435 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; ISS:GeneDB_Pfalciparum. 
Interpro
 IPR005937; 26S_Psome_P45.
 IPR003593; AAA+_ATPase.
 IPR003959; ATPase_AAA_core.
 IPR003960; ATPase_AAA_CS.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00004; AAA 
SMART
 SM00382; AAA 
PROSITE
 PS00674; AAA 
PRINTS