UniProt Accession

 TALA_ECOLI; P0A867; P78258; P80218 

Genbank Protein ID

 D13159; U00096; AP009048 

Genbank Nucleotide ID

 BAA21821.1; AAC75517.1; BAA16339.1 

Protein Name

 Transaldolase A 

Protein Synonyms/Alias

  

Gene Name

 talA 

Gene Synonyms/Alias

 b2464; JW2448 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
40	TNPSLLLKAAGLSQY	acetylation	[1]
59	DDAIAWGKKNGKTQE	acetylation	[1]
86	NFGAEILKIVPGRVS	acetylation	[1]
104	DARLSFDKEKSIEKA	acetylation	[1]
106	RLSFDKEKSIEKARH	acetylation	[1]
125	YQQQGVEKSRILIKL	acetylation	[1]
189	YDWYQARKPMDPYVV	acetylation	[1, 2]
203	VEEDPGVKSVRNIYD	acetylation	[1]
249	TIAPNLLKELQEKVS	acetylation	[1, 2]
254	LLKELQEKVSPVVRK	acetylation	[1]
293	QDAMAVEKLSEGIRL	acetylation	[1]
307	LFAVDQRKLEDLLAA	acetylation	[1, 2]
315	LEDLLAAKL******	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618]
 [2] Comprehensive profiling of protein lysine acetylation in Escherichia coli.
 Zhang K, Zheng S, Yang JS, Chen Y, Cheng Z.
 J Proteome Res. 2013 Feb 1;12(2):844-51. [PMID: 23294111] 

Functional Description

 Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. 

Sequence Annotation

 ACT_SITE 131 131 Schiff-base intermediate with substrate  

Keyword

 Complete proteome; Cytoplasm; Pentose shunt; Reference proteome; Schiff base; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 316 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004801; F:sedoheptulose-7-phosphate:D-glyceraldehyde-3-phosphate glyceronetransferase activity; IEA:HAMAP.
 GO:0006098; P:pentose-phosphate shunt; IEA:HAMAP. 

Interpro

 IPR013785; Aldolase_TIM.
 IPR001585; Transaldolase.
 IPR004730; Transaldolase_1.
 IPR018225; Transaldolase_AS. 

Pfam

 PF00923; Transaldolase 

SMART

  

PROSITE

 PS01054; TRANSALDOLASE_1
 PS00958; TRANSALDOLASE_2 

PRINTS