CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025768
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MKIAA4131 protein 
Protein Synonyms/Alias
  
Gene Name
 Dgkg 
Gene Synonyms/Alias
 mKIAA4131 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
440LLVLVNPKSGGRQGEubiquitination[1]
775MMMGPPQKSSFFSLRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 789 AA 
Protein Sequence
KMSEEQWVSL SSEEFDQLQK YSEYSSKKIK DVLAEFNEGG SLRQYDPHKP ISYDVFKLFM 60
RAYLEVDLPQ PLSTHLFLAF SQKPRQETPD HPKEGASSSE PNVSDYNSDN AAKADEACAP 120
DTESKTTKTQ APSKELEAAA PWEDPGALAS SSDAPVVYLK DVVCYLSLME TGRPQDKLEF 180
MFRLYDSDEN GLLDQAEMDQ IVSQMLHVAQ YLEWDPTELR PILKEMLQGM DYDKDGFVSL 240
QEWINGGMTT IPLLVLLGMD DSGSKGDGRH AWTLKHFKKP TYCNFCRAML MGVGKQGLCC 300
IYCKYTVHQR CVSKTIHGCV KTNSKAKRSG EVMQHAWVEG NSSVKCDRCH KSIKCYQSVT 360
ARHCVWCRMT FHRKCELSTV CDGGELKDHI LLPTSICPVS GDRQGGKSDG SVAAKGELVT 420
QYKIIPSPGT HPLLVLVNPK SGGRQGERIL RKFHYLLNPE QVFNLDNGGP TPGLNFFHDT 480
PDFRVLACGG DGTVGWILDC IDKANFTKHP PVAVLPLGTG NDLARCLRWG GGYEGGSLTK 540
ILKEIEQSPL VMLDRWYLEV MPREEVENGD QVPYNIMNNY FSIGVDASIA HRFHMMREKH 600
PEKFNSRMKN KLWYFEFGTS ETFAATCKKL HDHIELECDG VEVDLSNIFL EGIAILNIPS 660
MYGGTNLWGE TKKNRAVIRE SRKSVTDPKE LKCCVQDLSD QLLEVVGLEG AMEMGQIYTG 720
LKSAGRRLAQ CSSVTIRTNK LLPMQVDGEP WMQPQCTIKI THKNQAPMMM GPPQKSSFFS 780
LRRKSRSKD 789 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004143; F:diacylglycerol kinase activity; IEA:Compara.
 GO:0035556; P:intracellular signal transduction; IEA:InterPro.
 GO:0048666; P:neuron development; IEA:Compara.
 GO:0007205; P:protein kinase C-activating G-protein coupled receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR000756; Diacylglycerol_kin_accessory.
 IPR001206; Diacylglycerol_kinase_cat_dom.
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR002219; Prot_Kinase_C-like_PE/DAG-bd. 
Pfam
 PF00130; C1_1
 PF00609; DAGK_acc
 PF00781; DAGK_cat
 PF13499; EF_hand_5 
SMART
 SM00109; C1
 SM00045; DAGKa
 SM00046; DAGKc
 SM00054; EFh 
PROSITE
 PS50146; DAGK
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS00479; ZF_DAG_PE_1
 PS50081; ZF_DAG_PE_2 
PRINTS