CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034555
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein Brwd3 
Protein Synonyms/Alias
  
Gene Name
 Brwd3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
1548RNRVLPAKQDHSLDGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1800 AA 
Protein Sequence
MAAAPTQIEA ELYYLIARFL QSGPCNKSAQ VLVQELEEHQ LIPRRLDWEG KEHRRSFEDL 60
VAANAHIPPD YLLKICERIG PLLDKEIPQS VPGVQTLLGV GRQSLLRDAK DCKNTLWNGS 120
AFAALHRGRP PELPVNYVKP PNVVNITSAR QLTGCSRFSH VFPSSAYQHI KMHKRILGHL 180
SSVYCVAFDR SGRRIFTGSD DCLVKIWATD DGRLLATLRG HSAEISDMAV NYENTLIAAG 240
SCDKVVRVWC LRTCAPVAVL QGHSASITSI QFCPSTKGTT RYLTSTGADG TICFWQWHVK 300
TMKFRDRPVK FTERSRPGVQ ISCSSFSSGG MFITTGSTDH VIRIYYLGSE IPEKIAELES 360
HTVRAKAEPF FNIASSLRFV SGSRDGTARI WQYQQQEWKS IVLDMATKMS GNNLTSTEDK 420
VTKLKVTMVA WDRYDTTVIT AVNNFLLKVW NSVTGQLLHT LSGHDDEVFV LEAHPFDQRI 480
ILSAGHDGNI FIWDLDRGTK IRNYFNMIEG QGHGAVFDCK FSPDGNHFAC TDSHGHLLLF 540
GFGCSKYYEK IPDQMFFHTD YRPLIRDANN YVLDEQTQQA PHLMPPPFLV DVDGNPHPTK 600
FQRLVPGREN CKDEQLIPQL GYVANGDGEV VEQVIGQQTN DQEESILDGI IRELQREQDL 660
RLINEGDVPH FPINRSYSVN GALSSPNMDI PSSPNIGLRR SGQIEGVRQM HNNAPRSQMA 720
TERDLMAWSR RVVVNELNSG VSRVQEECRN AKGDLEVSLY TVEKKKKPSY PIQRNDYQPS 780
CGRSLRRTQR KRQHTYLTRS NIEHNSQASS QNSGVQGDSD SSSEEDETVG TSDASAEDPV 840
VEWQSESSSS DSSSEYSDWT ADAGINLQPP KRQTRQATQK IYSSSEDENV KSSEDRQKKP 900
KQTRKKKGGL VSMAGEPNEE WLAPQWILDT IPRRSPFVPQ MGDELIYFRQ GHEAYVRAVR 960
KSKIYSVNLQ KQPWNKMDLR EQEFVKIVGI KYEIGPPTLC CLKLAFLDPI SGKMTGESFS 1020
IKYHDMPDVI DFLVLHQFYN EAKERNWQIG DRFRSIIDDA WWFGTVESQQ PFQPEYPDSS 1080
FQCYSVHWDN NEREKMSPWD MEPIPEGTAF PDEVGAGIPV SQEELTALLY KPQEGEWGAH 1140
SRDEECERVI QGINNLLSLD FASPFAVPVD LSAYPLYCTV VAYPTDLNTI KQRLENRFYR 1200
RISALMWEVR YIEHNARTFN EPDSPIVKAA KIVTDVLLRF IGDQSCTDIL DTYNKIKAEN 1260
PNSSDPEEDT EMVDLDSDGP GTSSGRRAKC RGRRQSLKCN PDAWKQQCKE LLSLIYERED 1320
SEPFRQPADP HSHPVAQQQE GESSESVPPD RQDPSLSEDY QDVVDTPMDF STVKETLESG 1380
NYDSPLEFYK DVRQIFSNSK AYTSNKKSRI YSMTLRLSAL FENRIKNIIS EYKSAIQSQK 1440
RRRPRYRKRL RSSSSSLSSS RAPSPKGKQK QMKLQPKNDQ NTSVVYARTS SPFSSPVSDA 1500
AEGVSLYLLD DEGDGPFSPS SCSGYSRSGN SHDPGKAKSF RNRVLPAKQD HSLDGPLTNV 1560
DGREPRTGAK RKLLSASEED ESMGGEEKEM KETKEKAHLS SSESGELGSS LSSESTSGSD 1620
SDSESTSRTD QDYVDGDHDY SKFIQTRPKR KLRRQHATGK RNWKTRGTGG RGRWGRWGRW 1680
SRGGRGRGGR GRGGRGRGGG GGRGRGRGRG GRGASRGASR TKRARVADDE FDTMFAGRFS 1740
RLPRIKTRNQ GRRTVLYNDD SDNDNFVSTE DPLNLGTSRS GRVRKMTEKA RVSHLMGWNY 1800 
Gene Ontology
  
Interpro
 IPR001487; Bromodomain.
 IPR011044; Quino_amine_DH_bsu.
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR019775; WD40_repeat_CS.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00439; Bromodomain
 PF00400; WD40 
SMART
 SM00297; BROMO
 SM00320; WD40 
PROSITE
 PS50014; BROMODOMAIN_2
 PS00678; WD_REPEATS_1
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS
 PR00503; BROMODOMAIN.