| Tag | Content |
|---|
| CPLM ID | CPLM-019102 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | TBC1 domain family member 20 |
Protein Synonyms/Alias | |
Gene Name | TBC1D20 |
Gene Synonyms/Alias | C20orf140 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 112 | DPPPISGKNLRQMSK | ubiquitination | [1] | | 351 | RTAASTFKDFELASA | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May act as a GTPase-activating protein for Rab family protein(s). |
Sequence Annotation | DOMAIN 60 246 Rab-GAP TBC. |
Keyword | 3D-structure; Alternative splicing; Complete proteome; GTPase activation; Host-virus interaction; Membrane; Polymorphism; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 403 AA |
Protein Sequence | MPSGCYVPRS EPRLLPAPPP AGARVGALRS AQGDGPTSGH WDGGAEKADF NAKRKKKVAE 60
IHQALNSDPT DVAALRRMAI SEGGLLTDEI RRKVWPKLLN VNANDPPPIS GKNLRQMSKD 120
YQQVLLDVRR SLRRFPPGMP EEQREGLQEE LIDIILLILE RNPQLHYYQG YHDIVVTFLL 180
VVGERLATSL VEKLSTHHLR DFMDPTMDNT KHILNYLMPI IDQVNPELHD FMQSAEVGTI 240
FALSWLITWF GHVLSDFRHV VRLYDFFLAC HPLMPIYFAA VIVLYREQEV LDCDCDMASV 300
HHLLSQIPQD LPYETLISRA GDLFVQFPPS ELAREAAAQQ QAERTAASTF KDFELASAQQ 360
RPDMVLRQRF RGLLRPEDRT KDVLTKPRTN RFVKLAVMGL TVALGAAALA VVKSALEWAP 420
KFQLQLFP 428 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005622; C:intracellular; IEA:InterPro. GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. GO:0019048; P:virus-host interaction; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |