Tag | Content |
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CPLM ID | CPLM-008834 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Erythrocyte band 7 integral membrane protein |
Protein Synonyms/Alias | Protein 7.2b; Stomatin |
Gene Name | Stom |
Gene Synonyms/Alias | Epb7.2; Epb72 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
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198 | RVEIKDVKLPVQLQR | ubiquitination | [1] | 220 | AAREARAKVIAAEGE | ubiquitination | [1] | 235 | MNASRALKEASMVIT | ubiquitination | [1] |
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Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Thought to regulate cation conductance. May regulate ASIC2 and ASIC3 gating. |
Sequence Annotation | REGION 265 273 Required for homooligomerization (By REGION 267 269 Required for lipid raft association (By REGION 273 284 Interaction with LANCL1 (By similarity). MOD_RES 161 161 Phosphoserine. MOD_RES 244 244 Phosphoserine. LIPID 30 30 S-palmitoyl cysteine (By similarity). LIPID 87 87 S-palmitoyl cysteine (By similarity). |
Keyword | 3D-structure; Cell membrane; Complete proteome; Lipoprotein; Membrane; Palmitate; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 284 AA |
Protein Sequence | MSDKRQSSHV QSQRIPESFR ENSKTELGAC GWILVAASFF FVIITFPISI WICIKIVKEY 60 ERVIIFRLGR ILQGGAKGPG LFFILPCTDS LIKVDMRTIS FDIPPQEVLT KDSVTISVDG 120 VVYYRVQNAT LAVANITNAD SATRLLAQTT LRNALGTKNL SQILSDREEI AHHMQSTLDD 180 ATDDWGIKVE RVEIKDVKLP VQLQRAMAAE AEAAREARAK VIAAEGEMNA SRALKEASMV 240 ITESPAALQL RYLQTLTTIA AEKNSTIVFP LPVDMLQGIM GSNH 284 |
Gene Ontology | GO:0005856; C:cytoskeleton; ISS:UniProtKB. GO:0070062; C:extracellular vesicular exosome; IEA:Compara. GO:0005887; C:integral to plasma membrane; ISS:UniProtKB. GO:0042470; C:melanosome; IEA:UniProtKB-SubCell. GO:0045121; C:membrane raft; ISS:UniProtKB. GO:0051260; P:protein homooligomerization; ISS:UniProtKB. |
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