| Tag | Content |
|---|
| CPLM ID | CPLM-045125 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Megakaryocyte-associated tyrosine kinase, isoform CRA_a |
Protein Synonyms/Alias | Megakaryocyte-associated tyrosine-protein kinase |
Gene Name | MATK |
Gene Synonyms/Alias | hCG_23522 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 217 | PKRKHGTKSAEEELA | ubiquitination | [1] | | 375 | VSDFGLAKAERKGLD | ubiquitination | [1] | | 438 | EVSEAVEKGYRMEPP | ubiquitination | [1] |
|
Reference | [1] Global identification of modular cullin-RING ligase substrates. Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ. Cell. 2011 Oct 14;147(2):459-74. [ PMID: 21963094] |
Functional Description | |
Sequence Annotation | |
Keyword | ATP-binding; Complete proteome; Kinase; Nucleotide-binding; Reference proteome; SH3 domain; Transferase; Tyrosine-protein kinase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 506 AA |
Protein Sequence | MAGRGSLVSW RAFHGCDSAE ELPRVSPRFL RAWHPPPVSA RMPTRRWAPG TQCITKCEHT 60
RPKPGELAFR KGDVVTILEA CENKSWYRVK HHTSGQEGLL AAGALREREA LSADPKLSLM 120
PWFHGKISGQ EAVQQLQPPE DGLFLVRESA RHPGDYVLCV SFGRDVIHYR VLHRDGHLTI 180
DEAVFFCNLM DMVEHYSKDK GAICTKLVRP KRKHGTKSAE EELARAGWLL NLQHLTLGAQ 240
IGEGEFGAVL QGEYLGQKVA VKNIKCDVTA QAFLDETAVM TKMQHENLVR LLGVILHQGL 300
YIVMEHVSKG NLVNFLRTRG RALVNTAQLL QFSLHVAEGM EYLESKKLVH RDLAARNILV 360
SEDLVAKVSD FGLAKAERKG LDSSRLPVKW TAPEALKHGF TSKSDVWSFG VLLWEVFSYG 420
RAPYPKMSLK EVSEAVEKGY RMEPPEGCPG PVHVLMSSCW EAEPARRPPF RKLAEKLARE 480
LRSAGAPASV SGQDADGSTS PRSQEP 506 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0004713; F:protein tyrosine kinase activity; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |