UniProt Accession

 F6VW30_MOUSE; F6VW30 

Genbank Protein ID

 AC140457 

Genbank Nucleotide ID

  

Protein Name

 14-3-3 protein theta 

Protein Synonyms/Alias

  

Gene Name

 Ywhaq 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
61	SPSLAMEKTELIQKA	acetylation	[1]
67	EKTELIQKAKLAEQA	acetylation	[1]
67	EKTELIQKAKLAEQA	ubiquitination	[2]
69	TELIQKAKLAEQAER	ubiquitination	[2]
107	NLLSVAYKNVVGGRR	acetylation	[1]
107	NLLSVAYKNVVGGRR	ubiquitination	[2]
126	VISSIEQKTDTSDKK	ubiquitination	[2]
132	QKTDTSDKKLQLIKD	ubiquitination	[2]
138	DKKLQLIKDYREKVE	acetylation	[1]
138	DKKLQLIKDYREKVE	ubiquitination	[2]
143	LIKDYREKVESELRS	ubiquitination	[2]
173	NATNPESKVFYLKMK	acetylation	[1, 3]
173	NATNPESKVFYLKMK	ubiquitination	[2]
178	ESKVFYLKMKGDYFR	ubiquitination	[2]
180	KVFYLKMKGDYFRYL	ubiquitination	[2]
197	VACGDDRKQTIENSQ	ubiquitination	[2]
215	QEAFDISKKEMQPTH	ubiquitination	[2]
216	EAFDISKKEMQPTHP	acetylation	[1]
216	EAFDISKKEMQPTHP	ubiquitination	[2]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 303 AA 

Protein Sequence

Gene Ontology

 GO:0019904; F:protein domain specific binding; IDA:MGI.
 GO:0006605; P:protein targeting; IDA:MGI.
 GO:0007264; P:small GTPase mediated signal transduction; IPI:MGI. 

Interpro

 IPR000308; 14-3-3.
 IPR023409; 14-3-3_CS.
 IPR023410; 14-3-3_domain. 

Pfam

 PF00244; 14-3-3 

SMART

 SM00101; 14_3_3 

PROSITE

 PS00796; 1433_1
 PS00797; 1433_2 

PRINTS

 PR00305; 1433ZETA.