CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-035838
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Centaurin beta 2 
Protein Synonyms/Alias
  
Gene Name
 Acap2 
Gene Synonyms/Alias
 centb2 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
57KAFCVANKQFMNGIRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Metal-binding; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 777 AA 
Protein Sequence
MKMTVDFEEC LKDSPRFRAA LEEVEGDVAE LELKLDKLVK LCIAMIDTGK AFCVANKQFM 60
NGIRDLAQYS SNDAVVETSL TKFSDSLQEM INFHTILFDQ TQRSIKAQLQ NFVKEDLRKF 120
KDAKKQFEKV SEEKENALVK NAQVQRNKQH EVEEAANILT ATRKCFRHIA LDYVLQINVL 180
QSKRRSEILK SMLSFMYAHL AFFHQGYDLF SELGPYMKDL GAQLDRLVVD AAKEKREMEQ 240
KHSTIQQKDF SSDDSKLEYN VDAANGIVME GYLFKRASNA FKTWNRKKPD HIRRWFSIQN 300
NQLVYQKKFK DSPTVVVEDL RLCTVKHCED IERRFCFEVV SPTKSCMLQA DSEKLRQAWI 360
KAVQTSIATA YREKGDESEK LDKKSSPSTG SLDSGNESKE KLLKGESALQ RVQCIPGNTS 420
CCDCGLADPR WASINLGITL CIECSGIHRS LGVHFSKVRS LTLDTWEPEL LKLMCELGND 480
VINRVYEAKL EKMGVKKPQP GQRQEKEAYI RAKYVERKFV DKYSALLSPS EQEKRIISKS 540
CEDQRLSHAR ASVHTPVKSN DSGIQQCSED GRESLPSTVS ANSLYEPEGE RQESSVFLDS 600
KHLNPGLQLY RASYEKNLPK MAEALAHGAD VNWANSDENQ ATPLIQAVLG GSLVTCEFLL 660
QNGANVNQRD VQGRGPLHHA TVLGHTGQVC LFLKRGANQH ATDEEGKDPL SIAVEAANAD 720
IVTLLRLARM NEEMRESEGL YGQPGDETYQ DIFRDFSQMA SNNPEKLNRF QQDSQKF 777 
Gene Ontology
 GO:0008060; F:ARF GTPase activator activity; IEA:InterPro.
 GO:0005543; F:phospholipid binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0032312; P:regulation of ARF GTPase activity; IEA:InterPro. 
Interpro
 IPR027267; AH/BAR-dom.
 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR001164; ArfGAP.
 IPR011993; PH_like_dom.
 IPR001849; Pleckstrin_homology. 
Pfam
 PF12796; Ank_2
 PF01412; ArfGap
 PF00169; PH 
SMART
 SM00248; ANK
 SM00105; ArfGap
 SM00233; PH 
PROSITE
 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS50115; ARFGAP
 PS50003; PH_DOMAIN 
PRINTS
 PR00405; REVINTRACTNG.