CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041770
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cysteinyl-tRNA synthetase (Predicted), isoform CRA_b 
Protein Synonyms/Alias
 Protein Cars 
Gene Name
 Cars 
Gene Synonyms/Alias
 Cars_predicted; rCG_47503 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
48VFIPQDGKKVTWYCCacetylation[1]
148SETTDPDKRQMLERIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Aminoacyl-tRNA synthetase; Complete proteome; Ligase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 748 AA 
Protein Sequence
MAGSSAEQGK GRRVQPQWSP PAGTEPCRLR LYNSLTRNKD VFIPQDGKKV TWYCCGPTVY 60
DASHMGHARS YISFDILRRV LRDYFQYDVF YCMNITDIDD KIIRRARQNY LFEQYREQKP 120
SAAQLLKDVG DAMKPFSVKL SETTDPDKRQ MLERIQNSVK LATEPLEQAV HSNPSGEEVD 180
SRVQVLLEEA KDLLSDWLDS TGGSEVTDNS IFSKLPKFWE EEFHKDMEAL NVLPPDVLTR 240
VSEYVPEIVN FVQKIVDNGY GYASNGSVYF DTAKFAASEK HSYGKLVPEA VGDQKALQEG 300
EGDLSISADR LSEKRSPNDF ALWKASKPGE PSWPCPWGKG RPGWHIECSA MAGSLLGASM 360
DIHGGGFDLR FPHHDNELAQ SEAYFENDCW VRYFLHTGHL TIAGCKMSKS LKNFITIKDA 420
LKKHSARQLR LAFLMHSWKD TLDYSSNTME SALQYEKFMN EFFLNVKDIL RAPVDITGQF 480
EKWEAEEVEL NKNFYDKKTA VHEALCDNID TRTVMEEMRA LVSQCNLYMA ARKAARRRPN 540
RALLENIAMY LTHMLKIFGA IEEENPLGFP VGGPGTNLNL ESTVMPYLQV LSEFREGVRK 600
IAREKKVLEV LQLSDALRDD ILPELGVRFE DHEGLPTVVK LVDRDTLLKE KEEKKRAEEE 660
KRRKKEEAAR KKQEQEAAKL AKMKTPPSEM FRSETDKYSK FDENGLPTHD TEGKELSKGQ 720
TKKLKKLFEA QEKVYKEYLQ QLQNSSLQ 748 
Gene Ontology
 GO:0005829; C:cytosol; IBA:RefGenome.
 GO:0005524; F:ATP binding; IEA:Compara.
 GO:0004817; F:cysteine-tRNA ligase activity; IBA:RefGenome.
 GO:0000049; F:tRNA binding; IEA:Compara.
 GO:0006423; P:cysteinyl-tRNA aminoacylation; IBA:RefGenome. 
Interpro
 IPR015803; Cys-tRNA-ligase.
 IPR024909; Cys-tRNA/MSH_ligase.
 IPR014729; Rossmann-like_a/b/a_fold.
 IPR009080; tRNAsynth_1a_anticodon-bd. 
Pfam
 PF01406; tRNA-synt_1e 
SMART
  
PROSITE
  
PRINTS
 PR00983; TRNASYNTHCYS.