CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025742
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome P450, family 39, subfamily a, polypeptide 1, isoform CRA_c 
Protein Synonyms/Alias
  
Gene Name
 Cyp39a1 
Gene Synonyms/Alias
 mCG_114883 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
179ATLNTLFKKGLFLTDubiquitination[1]
187KGLFLTDKRTIKEFYubiquitination[1]
191LTDKRTIKEFYQQFKubiquitination[1]
313SVFGTAGKDKIKVSEubiquitination[1]
387FPEPESFKPERWKEAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
 METAL 415 415 Iron (heme axial ligand) (By similarity).  
Keyword
 Heme; Iron; Metal-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 470 AA 
Protein Sequence
MGIMELFSPI AIAVLGSCVL FLFSRLKNLL GPPCIQGWIP WIGAGLEFGK APLEFIEKAR 60
IKYGPVFTIF AMGNRMTFVS EEEGINVLLK SEHVDFESAV QSPVYHTAWI PKNVFSALHE 120
RLYALMKGKM GTFNTHHFTG PLTEELHEQL EGLGTHGTMD LNDFVRYLLY PATLNTLFKK 180
GLFLTDKRTI KEFYQQFKTY DEGFEYGSQL PEWLLRNWSK SKRWLLALFE KNIGNIKAHG 240
SAGHSGTLLQ AILEVVETET RQYSPNYGLV VLWAALANAP PIAFWTLGYI LSHPDIHRTV 300
LESISSVFGT AGKDKIKVSE DDLKKLLIIK WCILESVRLR APGVITRKVV KPVKILNHTV 360
PSGDLLMLSP FWLHRNPKYF PEPESFKPER WKEANLDKYI FLDYFMAFGG GKFQCPGRWF 420
ALLEIQLCII LVLYKYECSL LDPLPKQSSR HLVGVPQPAG KCRIEYKQRA 470 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0008396; F:oxysterol 7-alpha-hydroxylase activity; IEA:Compara.
 GO:0008387; F:steroid 7-alpha-hydroxylase activity; IDA:MGI.
 GO:0006699; P:bile acid biosynthetic process; IEA:Compara.
 GO:0006707; P:cholesterol catabolic process; IDA:MGI. 
Interpro
 IPR001128; Cyt_P450.
 IPR024204; Cyt_P450_CYP7A1-type.
 IPR002403; Cyt_P450_E_grp-IV. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
  
PRINTS
 PR00465; EP450IV.