CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024827
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Nonstructural protein Rep78 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Adeno-associated virus - 6 
NCBI Taxa ID
 68558 
Lysine Modification
Position
Peptide
Type
References
84LFFVQFEKGESYFHLsumoylation[1]
447PLQDRMFKFELTRRLsumoylation[1]
Reference
 [1] SUMO-1 modification regulates the protein stability of the large regulatory protein Rep78 of adeno associated virus type 2 (AAV-2).
 Weger S, Hammer E, Heilbronn R.
 Virology. 2004 Dec 5;330(1):284-94. [PMID: 15527853] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 623 AA 
Protein Sequence
MPGFYEIVIK VPSDLDEHLP GISDSFVNWV AEKEWELPPD SDMDLNLIEQ APLTVAEKLQ 60
RDFLVQWRRV SKAPEALFFV QFEKGESYFH LHILVETTGV KSMVLGRFLS QIRDKLVQTI 120
YRGIEPTLPN WFAVTKTRNG AGGGNKVVDE CYIPNYLLPK TQPELQWAWT NMEEYISACL 180
NLAERKRLVA HDLTHVSQTQ EQNKENLNPN SDAPVIRSKT SARYMELVGW LVDRGITSEK 240
QWIQEDQASY ISFNAASNSR SQIKAALDNA GKIMALTKSA PDYLVGPAPP ADIKTNRIYR 300
ILELNGYDPA YAGSVFLGWA QKRFGKRNTI WLFGPATTGK TNIAEAIAHA VPFYGCVNWT 360
NENFPFNDCV DKMVIWWEEG KMTAKVVESA KAILGGSKVR VDQKCKSSAQ IDPTPVIVTS 420
NTNMCAVIDG NSTTFEHQQP LQDRMFKFEL TRRLEHDFGK VTKQEVKEFF RWAQDHVTEV 480
AHEFYVRKGG ANKRPAPDDA DKSEPKRACP SVADPSTSDA EGAPVDFADR YQNKCSRHAG 540
MLQMLFPCKT CERMNQNFNI CFTHGTRDCS ECFPGVSESQ PVVRKRTYRK LCAIHHLLGR 600
APEIACSACD LVNVDLDDCV SEQ 623 
Gene Ontology
 GO:0019079; P:viral genome replication; IEA:InterPro. 
Interpro
 IPR014015; Helicase_SF3_DNA-vir.
 IPR027417; P-loop_NTPase.
 IPR001257; Parvovirus_NS1_helicase.
 IPR014835; Rep_N. 
Pfam
 PF01057; Parvo_NS1
 PF08724; Rep_N 
SMART
  
PROSITE
 PS51206; SF3_HELICASE_1 
PRINTS