CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-036435
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Inosine-5'-monophosphate dehydrogenase 1 
Protein Synonyms/Alias
  
Gene Name
 Impdh1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
172APAGVTLKEANEILQubiquitination[1]
185LQRSKKGKLPIVNDQubiquitination[1]
219LASKDSHKQLLCGAAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 231 AA 
Protein Sequence
MADYLISGGT GYVPEDGLTA QQLFANADGL TYNDFLILPG FIDFIADEVD LTSALTRKIT 60
LKTPLISSPM DTVTEADMAI AMALMGGIGF IHHNCTPEFQ ANEVRKVKKF EQGFITDPVV 120
LSPSHTVGDV LEAKIQHGFS GIPITATGTM GSKLVMTPRV ELVVAPAGVT LKEANEILQR 180
SKKGKLPIVN DQDELVAIIA RTDLKKNRDY PLASKDSHKQ LLCGAAVGTR E 231 
Gene Ontology
 GO:0003938; F:IMP dehydrogenase activity; IDA:MGI.
 GO:0046651; P:lymphocyte proliferation; IMP:MGI.
 GO:0006164; P:purine nucleotide biosynthetic process; IMP:MGI. 
Interpro
 IPR013785; Aldolase_TIM.
 IPR000644; Cysta_beta_synth_core.
 IPR005990; IMP_DH.
 IPR001093; IMP_DH_GMPRt. 
Pfam
 PF00571; CBS
 PF00478; IMPDH 
SMART
 SM00116; CBS 
PROSITE
 PS51371; CBS 
PRINTS