CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014325
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATP-binding cassette sub-family D member 2 
Protein Synonyms/Alias
 Adrenoleukodystrophy-related protein 
Gene Name
 Abcd2 
Gene Synonyms/Alias
 Aldr 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
615DVLSGGEKQRMGMARubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
 Probable transporter (By similarity). 
Sequence Annotation
 DOMAIN 107 399 ABC transmembrane type-1.
 DOMAIN 479 705 ABC transporter.
 NP_BIND 512 519 ATP (Potential).
 REGION 1 218 Interaction with PEX19 (By similarity).
 MOD_RES 58 58 Phosphoserine.
 CARBOHYD 190 190 N-linked (GlcNAc...) (Potential).
 CARBOHYD 227 227 N-linked (GlcNAc...) (Potential).  
Keyword
 ATP-binding; Complete proteome; Glycoprotein; Membrane; Nucleotide-binding; Peroxisome; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 741 AA 
Protein Sequence
MIHMLNAAAY RVKWTRSGAA KRAACLVAAA YALKTLYPII GKRLKQPGHR KAKAEAYSPA 60
ENREILHCTE IICKKPAPGL NAAFFKQLLE LRKILFPKLV TTETGWLCLH SVALISRTFL 120
SIYVAGLDGK IVKSIVEKKP RTFIIKLIKW LMIAIPATFV NSAIRYLECK LALAFRTRLV 180
DHAYETYFAN QTYYKVINMD GRLANPDQSL TEDIMMFSQS VAHLYSNLTK PILDVILTSY 240
TLIRTATSRG ASPIGPTLLA GLVVYATAKV LKACSPKFGS LVAEEAHRKG YLRYVHSRII 300
ANVEEIAFYR GHKVEMKQLQ KCYKALAYQM NLILSKRLWY IMIEQFLMKY VWSSCGLIMV 360
AIPIITATGF ADGDLEDGPK QAMVSDRTEA FTTARNLLAS GADAIERIMS SYKEITELAG 420
YTARVYNMFW VFDEVKRGIY KRTVTQEPEN HSKRGGNLEL PLSDTLAIKG TVIDVDHGII 480
CENVPIITPA GEVVASRLNF KVEEGMHLLI TGPNGCGKSS LFRILSGLWP VYEGVLYKPP 540
PQHMFYIPQR PYMSLGSLRD QVIYPDSADD MREKGYTDQD LERILHSVHL YHIVQREGGW 600
DAVMDWKDVL SGGEKQRMGM ARMFYHKPKY ALLDECTSAV SIDVEGKIFQ AAIGAGISLL 660
SITHRPSLWK YHTHLLQFDG EGGWRFEQLD TAIRLTLSEE KQKLESQLAG IPKMQQRLNE 720
LCKILGEDSV LKTIQTPEKT S 741 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0005778; C:peroxisomal membrane; IEA:UniProtKB-SubCell.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0016887; F:ATPase activity; IEA:InterPro.
 GO:0006200; P:ATP catabolic process; IEA:GOC.
 GO:0006635; P:fatty acid beta-oxidation; IMP:UniProtKB.
 GO:0032000; P:positive regulation of fatty acid beta-oxidation; IEA:Compara.
 GO:0006810; P:transport; IEA:UniProtKB-KW.
 GO:0042760; P:very long-chain fatty acid catabolic process; IEA:Compara. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR010509; ABC_Ald_N.
 IPR003439; ABC_transporter-like.
 IPR017871; ABC_transporter_CS.
 IPR017940; ABC_transporter_type1.
 IPR027417; P-loop_NTPase. 
Pfam
 PF06472; ABC_membrane_2
 PF00005; ABC_tran 
SMART
 SM00382; AAA 
PROSITE
 PS50929; ABC_TM1F
 PS00211; ABC_TRANSPORTER_1
 PS50893; ABC_TRANSPORTER_2 
PRINTS