UniProt Accession

 H5_CHICK; P02259 

Genbank Protein ID

 J00870; X00169 

Genbank Nucleotide ID

 AAA48798.1; CAA24994.1 

Protein Name

 Histone H5 

Protein Synonyms/Alias

  

Gene Name

  

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Gallus gallus (Chicken) 

NCBI Taxa ID

 9031 

Lysine Modification

Position	Peptide	Type	References
13	VLSPAPAKPKRVKAS	acetylation	[1]
151	KKSRASPKKAKKPKT	acetylation	[1]

Reference

 [1] Characterization of post-translational modifications of the linker histones H1 and H5 from chicken erythrocytes using mass spectrometry.
 Snijders AP, Pongdam S, Lambert SJ, Wood CM, Baldwin JP, Dickman MJ.
 J Proteome Res. 2008 Oct;7(10):4326-35. [PMID: 18754630] 

Functional Description

 Histone H5 performs the same function as H1, being necessary for the condensation of nucleosome chains into higher order structures, and replaces histone H1 in certain cells. 

Sequence Annotation

 DOMAIN 25 98 H15.
 MOD_RES 23 23 Phosphoserine (Probable).
 MOD_RES 30 30 Phosphoserine (Probable).
 MOD_RES 146 146 Phosphoserine (Probable).
 MOD_RES 167 167 Phosphoserine (Probable).  

Keyword

 3D-structure; Chromosome; Complete proteome; Direct protein sequencing; DNA condensation; DNA-binding; Nucleus; Phosphoprotein; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 190 AA 

Protein Sequence

Gene Ontology

 GO:0000786; C:nucleosome; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0030261; P:chromosome condensation; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 

Interpro

 IPR005818; Histone_H1/H5.
 IPR005819; Histone_H5.
 IPR011991; WHTH_DNA-bd_dom. 

Pfam

 PF00538; Linker_histone 

SMART

 SM00526; H15 

PROSITE

 PS51504; H15 

PRINTS

 PR00624; HISTONEH5.