| Tag | Content |
|---|
| CPLM ID | CPLM-001810 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Signal peptidase I |
Protein Synonyms/Alias | SPase I; Leader peptidase I |
Gene Name | lepB |
Gene Synonyms/Alias | b2568; JW2552 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 48 | AAGDSLDKATLKKVA | acetylation | [1] | | 146 | DPKLDYIKRAVGLPG | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | |
Sequence Annotation | ACT_SITE 91 91
ACT_SITE 146 146
MOD_RES 1 1 Blocked amino end (Met).
DISULFID 171 177 |
Keyword | 3D-structure; Cell inner membrane; Cell membrane; Complete proteome; Disulfide bond; Hydrolase; Membrane; Protease; Reference proteome; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 324 AA |
Protein Sequence | MANMFALILV IATLVTGILW CVDKFFFAPK RRERQAAAQA AAGDSLDKAT LKKVAPKPGW 60
LETGASVFPV LAIVLIVRSF IYEPFQIPSG SMMPTLLIGD FILVEKFAYG IKDPIYQKTL 120
IETGHPKRGD IVVFKYPEDP KLDYIKRAVG LPGDKVTYDP VSKELTIQPG CSSGQACENA 180
LPVTYSNVEP SDFVQTFSRR NGGEATSGFF EVPKNETKEN GIRLSERKET LGDVTHRILT 240
VPIAQDQVGM YYQQPGQQLA TWIVPPGQYF MMGDNRDNSA DSRYWGFVPE ANLVGRATAI 300
WMSFDKQEGE WPTGLRLSRI GGIH 324 |
Gene Ontology | GO:0016021; C:integral to membrane; IDA:EcoliWiki. GO:0005886; C:plasma membrane; IDA:EcoliWiki. GO:0008233; F:peptidase activity; IDA:EcoliWiki. GO:0008236; F:serine-type peptidase activity; IEA:InterPro. GO:0015643; F:toxic substance binding; IMP:EcoliWiki. GO:0016485; P:protein processing; IMP:EcoliWiki. GO:0006508; P:proteolysis; IDA:EcoliWiki. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |