UniProt Accession

 B5ME97_HUMAN; B5ME97 

Genbank Protein ID

 AC011753; AC140485; CH471182 

Genbank Nucleotide ID

 EAW53860.1 

Protein Name

 Septin 10, isoform CRA_c 

Protein Synonyms/Alias

 Septin-10 

Gene Name

 SEPT10 

Gene Synonyms/Alias

 hCG_27895 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
34	GSDDEQIKRENIRSL	ubiquitination	[1]
104	SHFCPNVKLKAQTYE	acetylation	[2]
106	FCPNVKLKAQTYELQ	ubiquitination	[3, 4]
195	TLDLLTMKNLDSKVN	ubiquitination	[3, 4]
200	TMKNLDSKVNIIPVI	ubiquitination	[3, 4]
209	NIIPVIAKADTVSKT	ubiquitination	[3, 4]
215	AKADTVSKTELQKFK	ubiquitination	[3, 4]
220	VSKTELQKFKIKLMS	ubiquitination	[3]
269	VGSMDEVKVGNKMVK	ubiquitination	[3, 4]
340	TDVGPENKPVSVQET	ubiquitination	[3]
351	VQETYEAKRHEFHGE	ubiquitination	[3]
422	EEIIAFSKKKATSEI	ubiquitination	[3, 4]

Reference

 [1] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [2] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [4] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 544 AA 

Protein Sequence

Gene Ontology

 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0007049; P:cell cycle; IEA:InterPro. 

Interpro

 IPR000038; Cell_div_GTP-bd.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00735; Septin 

SMART

  

PROSITE

  

PRINTS